Package index • ddir

All functions

basic_cyp_inhibition_risk(): Basic CYP inhibition risk

basic_cyp_inhibition_risk_table(): Basic CYP inhibition risk table

basic_cyp_tdi_risk(): Basic modeling of the CYP time-dependent inhibition risk

basic_cyp_tdi_risk_table(): Basic CYP time-dependent inhibition risk table

basic_ugt_inhibition_risk(): UGT inhibition risk

basic_ugt_inhibition_risk_table(): UGT inhibition risk table

compound_names_string(): Compound names as single string

conc_table(): Table of key perpetrator concentrations

cyp_induction_risk_summary(): Summary statement for CYP induction

cyp_induction_risk_summary(<list>): Summary statement for CYP induction for a list of precipitants

cyp_induction_risk_summary(<perpetrator>): Summary statement for CYP induction for a precipitant compound

cyp_inhibition_risk_summary(): Summary statement for CYP inhibition

cyp_inhibition_risk_summary(<list>): Summary statement for CYP inhibition for a list of perpetrators

cyp_inhibition_risk_summary(<perpetrator>): Summary statement for CYP inhibition for a precipitant compound

cyp_reference_substrates: CYP reference substrate data

cyp_tdi_risk_summary(): Summary statement for CYP TDI

cyp_tdi_risk_summary(<list>): Summary statement for CYP TDI for a list of compounds

cyp_tdi_risk_summary(<perpetrator>): Summary statement for CYP TDI for a precipitant compound

cyp_turnover: CYP turnover rate constants

ddi_report_template(): Open report template

ddi_risk_summary() experimental: Overall DDI risk summary text block

dose(): Oral dose

dose(<list>): Oral doses of compound list

dose(<perpetrator>): Oral dose of perpetrator

examplinib_compounds: Perpetrator compound data for examplinib and its metabolite

examplinib_compounds_single_string: Examplinib compound data for parent only as string

examplinib_compounds_string: Examplinib compound data as string

examplinib_cyp_induction_data: Examplinib CYP induction data

examplinib_cyp_induction_string: Examplinib CYP induction data as string

examplinib_cyp_inhibition_data: Examplinib CYP inhibition data

examplinib_cyp_inhibition_string: Examplinib CYP inhibitor data as string

examplinib_cyp_tdi_data: Examplinib CYP TDI data

examplinib_cyp_tdi_string: Examplinib CYP TDI data as string

examplinib_metabolite: Perpetrator compound data for examplinib

examplinib_parent: Perpetrator compound data for examplinib

examplinib_transporter_inhibition_data: Examplinib transporter inhibition data

examplinib_transporter_inhibition_string: Examplinib transporter inhibition data as string

examplinib_ugt_inhibition_data: Examplinib UGT inhibition data

examplinib_ugt_inhibition_string: Examplinib UGT inhibition data as string

hepatic_cyp_turnover deprecated: Hepatic CYP turnover data based on various publications

is_igut_solubility_limited(): Test if Igut of a perpetrator is limited by its solubility

key_concentrations(): Key perpetrator concentrations

kinetic_cyp_induction_risk(): Basic kinetic CYP induction risk

kinetic_cyp_induction_risk_table(): Table of the basic kinetic CYP induction risk

make_perpetrator(): Make a perpetrator object from compound data

mech_stat_cyp_risk(): CYP perpetration risk as per mechanistic-static modeling

mech_stat_cyp_risk_summary(): Summary statement for mechanistic-static modeling of CYP modulation

mech_stat_cyp_risk_summary(<list>): Summary statement for mechanistic-static modeling of CYP modulation

mech_stat_cyp_risk_summary(<perpetrator>): Summary statement for mechanistic-static modeling of CYP modulation

mech_stat_cyp_risk_table(): CYP perpetration risk table as per mechanistic-static modeling

new_perpetrator(): Perpetrator object constructor

property_table(): Table of perpetrator drug properties

read_cyp_inhibitor_data(): Read CYP inhibition data

read_inducer_data(): Read csv-formatted CYP inducer data

read_inhibitor_data() deprecated: Read csv-formatted CYP inhibition data

read_perpetrators(): Read perpetrator information from file or text string

read_tdi_data(): Read csv-formatted CYP TDI data

read_transporter_inhibitor_data(): Read transporter inhibition data

read_ugt_inhibitor_data(): Read UGT inhibition data

static_cyp_induction_risk(): Basic static CYP induction risk

static_cyp_induction_risk_table(): Table of the basic static CYP induction risk

transporter_inhibition_risk(): Drug transporter inhibition risk

transporter_inhibition_risk_summary(): Summary statement for transporter inhibition

transporter_inhibition_risk_summary(<list>): Summary statement for transporter inhibition for a list of compounds

transporter_inhibition_risk_summary(<perpetrator>): Summary statement for transporter inhibition for a precipitant compound

transporter_inhibition_risk_table(): Table of drug transporter inhibition risks

transporter_reference_data: Drug transporter reference data

ugt_inhibition_risk_summary(): Summary statement for UGT inhibition

ugt_inhibition_risk_summary(<list>): Summary statement for UGT inhibition for a list of compounds

ugt_inhibition_risk_summary(<perpetrator>): Summary statement for UGT inhibition for a precipitant compound