Kinetic assessment of CYP induction risk

Usage

kinetic_cyp_induction_risk(perp, cyp_ind, d = 1)

Arguments

perp: Precipitant object
cyp_ind: induction_data object.
d: Scaling factor, defaults to 1.

Value

DDI risk object

Examples

kinetic_cyp_induction_risk(examplinib, examplinib_cyp_induction)
#> ──────── Clinical DDI risk assessment ──────── 
#> Kinetic CYP induction risk for examplinib 
#> 
#> object    emax   ec50   max_c   source      r       risk   
#> CYP1A2    1      NA     5       study 007   NA      NA     
#> CYP2B6    1      NA     5       study 007   NA      NA     
#> CYP2C8    NA     NA     NA      NA          NA      NA     
#> CYP2C9    NA     NA     NA      NA          NA      NA     
#> CYP2C19   NA     NA     NA      NA          NA      NA     
#> CYP2D6    NA     NA     NA      NA          NA      NA     
#> CYP3A4    7.35   1.64   3       study 007   0.213   TRUE