CYP turnover rate constants

Mean degradation constants in 1/h for hepatic and intestinal CYP enzymes.

Usage

cyp_turnover

Format

A data frame with 3 columns

Source

This data set is taken from various literature sources

Details

    cyp kdeg_hepatic kdeg_intestinal
 CYP1A1       0.0183              NA
 CYP1A2       0.0183              NA
 CYP2A6       0.0267              NA
 CYP2B6       0.0217              NA
 CYP2C8       0.0301              NA
 CYP2C9       0.0067            0.03
CYP2C18       0.0267              NA
CYP2C19       0.0267            0.03
 CYP2D6       0.0099            0.03
 CYP2E1       0.0176              NA
 CYP2J2       0.0194            0.03
 CYP3A4       0.0193            0.03
 CYP3A5       0.0193            0.03
 CYP3A7       0.0193              NA

See also

basic_cyp_tdi_risk()

mech_stat_cyp_risk()