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Plot in vitro CYP induction data

induction_plot.Rd

Plot in vitro CYP induction data

Usage

induction_plot(x, type = "REL", log = TRUE)

Arguments

x

The in vitro data set as data frame. The following fields are expected:

  • DONOR The hepatocyte donor batch as character.

  • PRECIPITANT The DDI precipitant as character.

  • CONC The precipitant concentration.

  • OBJECT The DDI target object as character.

  • FOLD The mRNA or enzyme activity change at the respective precipitant concentration.

  • REL The mRNA or enzyme activity induction, as percent of positive control at the respective precipitant concentration.

FOLD and REL are optional but a column that corresponds to the 'type' argument must be present.

type

The DDI metric, e.g. FOLD or REL, as character. A different type can be given but a column of that name must be present in the data set.

log

Plot logarithmic x axis, as logical.

Value

A ggplot object.

Examples

induction_plot(examplinib_in_vitro_ind)

induction_plot(examplinib_in_vitro_ind, type = "FOLD")