Perform Non-Compartmental Analysis (NCA) for each subject and analyte

This function performs NCA analysis using the pknca package for each subject and analyte in a NIF object. It identifies administrations using the EVID field and calculates PK parameters for each dosing interval.

Usage

nif_nca_new(obj, analytes = NULL, parameters = NULL, keep = NULL)

Arguments

obj

A NIF object containing concentration-time data

analytes

Optional vector of analytes to analyze. If NULL, all analytes will be analyzed.

parameters

Optional vector of PK parameters to calculate. If NULL, default parameters will be used.

keep

Optional vector of additional columns to keep in the output.

Value

A long data frame containing NCA results with at least the fields USUBJID, PPTESTCD, ANALYTE, PPSTRESN

Examples

# nca_results <- nif_nca_new(nif_object)