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[Experimental]

Usage

nca1(
  nif,
  analyte = NULL,
  parent = NULL,
  keep = NULL,
  group = NULL,
  time = "TIME",
  average_duplicates = TRUE
)

Arguments

nif

A nif object.

analyte

The analyte as character.

parent

The parent as character.

keep

Columns to keep, as character.

group

Columns to group by, as character.

time

The time field as character.

average_duplicates

Average duplicate concentration values, as logical.

Value

A data frame.

Details

This function is a wrapper around the NCA functions provided by the PKNCA package.

Examples

nca1(examplinib_sad_nif, time = "TAD")
#> NCA: No analyte specified. Selected RS2023 as the most likely.
#>     ID DI start end            PPTESTCD      PPORRES exclude DOSE
#> 1    1  1     0  24             auclast 1.358359e+02    <NA>    5
#> 2    1  1     0 Inf                cmax 4.855300e+01    <NA>    5
#> 3    1  1     0 Inf                tmax 1.000000e+00    <NA>    5
#> 4    1  1     0 Inf               tlast 9.600000e+01    <NA>    5
#> 5    1  1     0 Inf           clast.obs 2.000000e-04    <NA>    5
#> 6    1  1     0 Inf            lambda.z 8.606345e-02    <NA>    5
#> 7    1  1     0 Inf           r.squared 9.995549e-01    <NA>    5
#> 8    1  1     0 Inf       adj.r.squared 9.993323e-01    <NA>    5
#> 9    1  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>    5
#> 10   1  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>    5
#> 11   1  1     0 Inf          clast.pred 1.896607e-04    <NA>    5
#> 12   1  1     0 Inf           half.life 8.053909e+00    <NA>    5
#> 13   1  1     0 Inf          span.ratio 8.939758e+00    <NA>    5
#> 14   1  1     0 Inf          aucinf.obs 1.369298e+02    <NA>    5
#> 15   2  1     0  24             auclast 1.272326e+02    <NA>    5
#> 16   2  1     0 Inf                cmax 4.242000e+01    <NA>    5
#> 17   2  1     0 Inf                tmax 1.000000e+00    <NA>    5
#> 18   2  1     0 Inf               tlast 9.600000e+01    <NA>    5
#> 19   2  1     0 Inf           clast.obs 1.000000e-04    <NA>    5
#> 20   2  1     0 Inf            lambda.z 9.577401e-02    <NA>    5
#> 21   2  1     0 Inf           r.squared 9.997482e-01    <NA>    5
#> 22   2  1     0 Inf       adj.r.squared 9.996223e-01    <NA>    5
#> 23   2  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>    5
#> 24   2  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>    5
#> 25   2  1     0 Inf          clast.pred 9.564347e-05    <NA>    5
#> 26   2  1     0 Inf           half.life 7.237320e+00    <NA>    5
#> 27   2  1     0 Inf          span.ratio 9.948434e+00    <NA>    5
#> 28   2  1     0 Inf          aucinf.obs 1.282302e+02    <NA>    5
#> 29   3  1     0  24             auclast 1.468552e+02    <NA>    5
#> 30   3  1     0 Inf                cmax 4.359650e+01    <NA>    5
#> 31   3  1     0 Inf                tmax 1.000000e+00    <NA>    5
#> 32   3  1     0 Inf               tlast 9.600000e+01    <NA>    5
#> 33   3  1     0 Inf           clast.obs 2.000000e-04    <NA>    5
#> 34   3  1     0 Inf            lambda.z 8.992019e-02    <NA>    5
#> 35   3  1     0 Inf           r.squared 9.997885e-01    <NA>    5
#> 36   3  1     0 Inf       adj.r.squared 9.996828e-01    <NA>    5
#> 37   3  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>    5
#> 38   3  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>    5
#> 39   3  1     0 Inf          clast.pred 2.070389e-04    <NA>    5
#> 40   3  1     0 Inf           half.life 7.708471e+00    <NA>    5
#> 41   3  1     0 Inf          span.ratio 9.340374e+00    <NA>    5
#> 42   3  1     0 Inf          aucinf.obs 1.483347e+02    <NA>    5
#> 43   4  1     0  24             auclast 2.351229e+02    <NA>   10
#> 44   4  1     0 Inf                cmax 7.640650e+01    <NA>   10
#> 45   4  1     0 Inf                tmax 1.000000e+00    <NA>   10
#> 46   4  1     0 Inf               tlast 9.600000e+01    <NA>   10
#> 47   4  1     0 Inf           clast.obs 2.000000e-04    <NA>   10
#> 48   4  1     0 Inf            lambda.z 9.370438e-02    <NA>   10
#> 49   4  1     0 Inf           r.squared 9.993040e-01    <NA>   10
#> 50   4  1     0 Inf       adj.r.squared 9.989560e-01    <NA>   10
#> 51   4  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>   10
#> 52   4  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>   10
#> 53   4  1     0 Inf          clast.pred 1.859780e-04    <NA>   10
#> 54   4  1     0 Inf           half.life 7.397170e+00    <NA>   10
#> 55   4  1     0 Inf          span.ratio 9.733453e+00    <NA>   10
#> 56   4  1     0 Inf          aucinf.obs 2.368426e+02    <NA>   10
#> 57   5  1     0  24             auclast 2.552607e+02    <NA>   10
#> 58   5  1     0 Inf                cmax 8.028810e+01    <NA>   10
#> 59   5  1     0 Inf                tmax 1.000000e+00    <NA>   10
#> 60   5  1     0 Inf               tlast 9.600000e+01    <NA>   10
#> 61   5  1     0 Inf           clast.obs 5.000000e-04    <NA>   10
#> 62   5  1     0 Inf            lambda.z 8.231758e-02    <NA>   10
#> 63   5  1     0 Inf           r.squared 9.999246e-01    <NA>   10
#> 64   5  1     0 Inf       adj.r.squared 9.998492e-01    <NA>   10
#> 65   5  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>   10
#> 66   5  1     0 Inf   lambda.z.n.points 3.000000e+00    <NA>   10
#> 67   5  1     0 Inf          clast.pred 4.950725e-04    <NA>   10
#> 68   5  1     0 Inf           half.life 8.420403e+00    <NA>   10
#> 69   5  1     0 Inf          span.ratio 5.700440e+00    <NA>   10
#> 70   5  1     0 Inf          aucinf.obs 2.576642e+02    <NA>   10
#> 71   6  1     0  24             auclast 2.037377e+02    <NA>   10
#> 72   6  1     0 Inf                cmax 6.989260e+01    <NA>   10
#> 73   6  1     0 Inf                tmax 1.000000e+00    <NA>   10
#> 74   6  1     0 Inf               tlast 9.600000e+01    <NA>   10
#> 75   6  1     0 Inf           clast.obs 1.000000e-04    <NA>   10
#> 76   6  1     0 Inf            lambda.z 1.006709e-01    <NA>   10
#> 77   6  1     0 Inf           r.squared 9.995714e-01    <NA>   10
#> 78   6  1     0 Inf       adj.r.squared 9.994285e-01    <NA>   10
#> 79   6  1     0 Inf lambda.z.time.first 1.200000e+01    <NA>   10
#> 80   6  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>   10
#> 81   6  1     0 Inf          clast.pred 1.060309e-04    <NA>   10
#> 82   6  1     0 Inf           half.life 6.885276e+00    <NA>   10
#> 83   6  1     0 Inf          span.ratio 1.219995e+01    <NA>   10
#> 84   6  1     0 Inf          aucinf.obs 2.051535e+02    <NA>   10
#> 85   7  1     0  24             auclast 5.178897e+02    <NA>   20
#> 86   7  1     0 Inf                cmax 1.724369e+02    <NA>   20
#> 87   7  1     0 Inf                tmax 1.000000e+00    <NA>   20
#> 88   7  1     0 Inf               tlast 9.600000e+01    <NA>   20
#> 89   7  1     0 Inf           clast.obs 6.000000e-04    <NA>   20
#> 90   7  1     0 Inf            lambda.z 9.033266e-02    <NA>   20
#> 91   7  1     0 Inf           r.squared 9.999737e-01    <NA>   20
#> 92   7  1     0 Inf       adj.r.squared 9.999605e-01    <NA>   20
#> 93   7  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>   20
#> 94   7  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>   20
#> 95   7  1     0 Inf          clast.pred 5.921746e-04    <NA>   20
#> 96   7  1     0 Inf           half.life 7.673273e+00    <NA>   20
#> 97   7  1     0 Inf          span.ratio 9.383218e+00    <NA>   20
#> 98   7  1     0 Inf          aucinf.obs 5.222793e+02    <NA>   20
#> 99   8  1     0  24             auclast 6.075938e+02    <NA>   20
#> 100  8  1     0 Inf                cmax 1.831545e+02    <NA>   20
#> 101  8  1     0 Inf                tmax 1.000000e+00    <NA>   20
#> 102  8  1     0 Inf               tlast 9.600000e+01    <NA>   20
#> 103  8  1     0 Inf           clast.obs 3.000000e-04    <NA>   20
#> 104  8  1     0 Inf            lambda.z 1.034840e-01    <NA>   20
#> 105  8  1     0 Inf           r.squared 9.999430e-01    <NA>   20
#> 106  8  1     0 Inf       adj.r.squared 9.999145e-01    <NA>   20
#> 107  8  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>   20
#> 108  8  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>   20
#> 109  8  1     0 Inf          clast.pred 2.937904e-04    <NA>   20
#> 110  8  1     0 Inf           half.life 6.698107e+00    <NA>   20
#> 111  8  1     0 Inf          span.ratio 1.074931e+01    <NA>   20
#> 112  8  1     0 Inf          aucinf.obs 6.125093e+02    <NA>   20
#> 113  9  1     0  24             auclast 4.797358e+02    <NA>   20
#> 114  9  1     0 Inf                cmax 1.529454e+02    <NA>   20
#> 115  9  1     0 Inf                tmax 1.000000e+00    <NA>   20
#> 116  9  1     0 Inf               tlast 9.600000e+01    <NA>   20
#> 117  9  1     0 Inf           clast.obs 3.000000e-04    <NA>   20
#> 118  9  1     0 Inf            lambda.z 9.909291e-02    <NA>   20
#> 119  9  1     0 Inf           r.squared 9.999927e-01    <NA>   20
#> 120  9  1     0 Inf       adj.r.squared 9.999855e-01    <NA>   20
#> 121  9  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>   20
#> 122  9  1     0 Inf   lambda.z.n.points 3.000000e+00    <NA>   20
#> 123  9  1     0 Inf          clast.pred 2.988914e-04    <NA>   20
#> 124  9  1     0 Inf           half.life 6.994922e+00    <NA>   20
#> 125  9  1     0 Inf          span.ratio 6.862121e+00    <NA>   20
#> 126  9  1     0 Inf          aucinf.obs 4.837786e+02    <NA>   20
#> 127 10  1     0  24             auclast 1.304964e+03    <NA>   50
#> 128 10  1     0 Inf                cmax 3.929893e+02    <NA>   50
#> 129 10  1     0 Inf                tmax 1.000000e+00    <NA>   50
#> 130 10  1     0 Inf               tlast 1.440000e+02    <NA>   50
#> 131 10  1     0 Inf           clast.obs 1.000000e-04    <NA>   50
#> 132 10  1     0 Inf            lambda.z 7.704916e-02    <NA>   50
#> 133 10  1     0 Inf           r.squared 9.999629e-01    <NA>   50
#> 134 10  1     0 Inf       adj.r.squared 9.999506e-01    <NA>   50
#> 135 10  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>   50
#> 136 10  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>   50
#> 137 10  1     0 Inf          clast.pred 1.020973e-04    <NA>   50
#> 138 10  1     0 Inf           half.life 8.996167e+00    <NA>   50
#> 139 10  1     0 Inf          span.ratio 1.333901e+01    <NA>   50
#> 140 10  1     0 Inf          aucinf.obs 1.318549e+03    <NA>   50
#> 141 11  1     0  24             auclast 2.517417e+03    <NA>   50
#> 142 11  1     0 Inf                cmax 7.695240e+02    <NA>   50
#> 143 11  1     0 Inf                tmax 1.000000e+00    <NA>   50
#> 144 11  1     0 Inf               tlast 1.440000e+02    <NA>   50
#> 145 11  1     0 Inf           clast.obs 1.000000e-04    <NA>   50
#> 146 11  1     0 Inf            lambda.z 8.471310e-02    <NA>   50
#> 147 11  1     0 Inf           r.squared 9.999778e-01    <NA>   50
#> 148 11  1     0 Inf       adj.r.squared 9.999704e-01    <NA>   50
#> 149 11  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>   50
#> 150 11  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>   50
#> 151 11  1     0 Inf          clast.pred 9.813760e-05    <NA>   50
#> 152 11  1     0 Inf           half.life 8.182291e+00    <NA>   50
#> 153 11  1     0 Inf          span.ratio 1.466582e+01    <NA>   50
#> 154 11  1     0 Inf          aucinf.obs 2.547796e+03    <NA>   50
#> 155 12  1     0  24             auclast 1.463739e+03    <NA>   50
#> 156 12  1     0 Inf                cmax 4.477305e+02    <NA>   50
#> 157 12  1     0 Inf                tmax 1.000000e+00    <NA>   50
#> 158 12  1     0 Inf               tlast 9.600000e+01    <NA>   50
#> 159 12  1     0 Inf           clast.obs 6.000000e-04    <NA>   50
#> 160 12  1     0 Inf            lambda.z 1.051391e-01    <NA>   50
#> 161 12  1     0 Inf           r.squared 9.999930e-01    <NA>   50
#> 162 12  1     0 Inf       adj.r.squared 9.999894e-01    <NA>   50
#> 163 12  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>   50
#> 164 12  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>   50
#> 165 12  1     0 Inf          clast.pred 5.990725e-04    <NA>   50
#> 166 12  1     0 Inf           half.life 6.592668e+00    <NA>   50
#> 167 12  1     0 Inf          span.ratio 1.092122e+01    <NA>   50
#> 168 12  1     0 Inf          aucinf.obs 1.474792e+03    <NA>   50
#> 169 13  1     0  24             auclast 4.774852e+03    <NA>  100
#> 170 13  1     0 Inf                cmax 1.189801e+03    <NA>  100
#> 171 13  1     0 Inf                tmax 1.500000e+00    <NA>  100
#> 172 13  1     0 Inf               tlast 9.600000e+01    <NA>  100
#> 173 13  1     0 Inf           clast.obs 4.800000e-03    <NA>  100
#> 174 13  1     0 Inf            lambda.z 9.949830e-02    <NA>  100
#> 175 13  1     0 Inf           r.squared 9.999706e-01    <NA>  100
#> 176 13  1     0 Inf       adj.r.squared 9.999559e-01    <NA>  100
#> 177 13  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  100
#> 178 13  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  100
#> 179 13  1     0 Inf          clast.pred 4.820410e-03    <NA>  100
#> 180 13  1     0 Inf           half.life 6.966422e+00    <NA>  100
#> 181 13  1     0 Inf          span.ratio 1.033529e+01    <NA>  100
#> 182 13  1     0 Inf          aucinf.obs 4.837404e+03    <NA>  100
#> 183 14  1     0  24             auclast 1.785177e+03    <NA>  100
#> 184 14  1     0 Inf                cmax 6.188954e+02    <NA>  100
#> 185 14  1     0 Inf                tmax 1.000000e+00    <NA>  100
#> 186 14  1     0 Inf               tlast 9.600000e+01    <NA>  100
#> 187 14  1     0 Inf           clast.obs 1.000000e-03    <NA>  100
#> 188 14  1     0 Inf            lambda.z 9.816547e-02    <NA>  100
#> 189 14  1     0 Inf           r.squared 9.999391e-01    <NA>  100
#> 190 14  1     0 Inf       adj.r.squared 9.999087e-01    <NA>  100
#> 191 14  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  100
#> 192 14  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  100
#> 193 14  1     0 Inf          clast.pred 9.816758e-04    <NA>  100
#> 194 14  1     0 Inf           half.life 7.061008e+00    <NA>  100
#> 195 14  1     0 Inf          span.ratio 1.019684e+01    <NA>  100
#> 196 14  1     0 Inf          aucinf.obs 1.796966e+03    <NA>  100
#> 197 15  1     0  24             auclast 3.239935e+03    <NA>  100
#> 198 15  1     0 Inf                cmax 1.063624e+03    <NA>  100
#> 199 15  1     0 Inf                tmax 1.000000e+00    <NA>  100
#> 200 15  1     0 Inf               tlast 1.440000e+02    <NA>  100
#> 201 15  1     0 Inf           clast.obs 1.000000e-04    <NA>  100
#> 202 15  1     0 Inf            lambda.z 8.576395e-02    <NA>  100
#> 203 15  1     0 Inf           r.squared 9.992598e-01    <NA>  100
#> 204 15  1     0 Inf       adj.r.squared 9.990131e-01    <NA>  100
#> 205 15  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  100
#> 206 15  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  100
#> 207 15  1     0 Inf          clast.pred 8.945041e-05    <NA>  100
#> 208 15  1     0 Inf           half.life 8.082034e+00    <NA>  100
#> 209 15  1     0 Inf          span.ratio 1.484775e+01    <NA>  100
#> 210 15  1     0 Inf          aucinf.obs 3.272423e+03    <NA>  100
#> 211 16  1     0  24             auclast 1.715794e+03    <NA>  100
#> 212 16  1     0 Inf                cmax 6.403108e+02    <NA>  100
#> 213 16  1     0 Inf                tmax 1.000000e+00    <NA>  100
#> 214 16  1     0 Inf               tlast 9.600000e+01    <NA>  100
#> 215 16  1     0 Inf           clast.obs 2.200000e-03    <NA>  100
#> 216 16  1     0 Inf            lambda.z 8.693226e-02    <NA>  100
#> 217 16  1     0 Inf           r.squared 9.999720e-01    <NA>  100
#> 218 16  1     0 Inf       adj.r.squared 9.999580e-01    <NA>  100
#> 219 16  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  100
#> 220 16  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  100
#> 221 16  1     0 Inf          clast.pred 2.229918e-03    <NA>  100
#> 222 16  1     0 Inf           half.life 7.973417e+00    <NA>  100
#> 223 16  1     0 Inf          span.ratio 9.030005e+00    <NA>  100
#> 224 16  1     0 Inf          aucinf.obs 1.729164e+03    <NA>  100
#> 225 17  1     0  24             auclast 2.804696e+03    <NA>  100
#> 226 17  1     0 Inf                cmax 9.528560e+02    <NA>  100
#> 227 17  1     0 Inf                tmax 1.000000e+00    <NA>  100
#> 228 17  1     0 Inf               tlast 9.600000e+01    <NA>  100
#> 229 17  1     0 Inf           clast.obs 7.000000e-04    <NA>  100
#> 230 17  1     0 Inf            lambda.z 1.126758e-01    <NA>  100
#> 231 17  1     0 Inf           r.squared 9.999370e-01    <NA>  100
#> 232 17  1     0 Inf       adj.r.squared 9.999161e-01    <NA>  100
#> 233 17  1     0 Inf lambda.z.time.first 1.200000e+01    <NA>  100
#> 234 17  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  100
#> 235 17  1     0 Inf          clast.pred 7.113547e-04    <NA>  100
#> 236 17  1     0 Inf           half.life 6.151693e+00    <NA>  100
#> 237 17  1     0 Inf          span.ratio 1.365478e+01    <NA>  100
#> 238 17  1     0 Inf          aucinf.obs 2.825315e+03    <NA>  100
#> 239 18  1     0  24             auclast 3.802874e+03    <NA>  100
#> 240 18  1     0 Inf                cmax 1.155409e+03    <NA>  100
#> 241 18  1     0 Inf                tmax 1.000000e+00    <NA>  100
#> 242 18  1     0 Inf               tlast 1.440000e+02    <NA>  100
#> 243 18  1     0 Inf           clast.obs 2.000000e-04    <NA>  100
#> 244 18  1     0 Inf            lambda.z 8.235036e-02    <NA>  100
#> 245 18  1     0 Inf           r.squared 9.999629e-01    <NA>  100
#> 246 18  1     0 Inf       adj.r.squared 9.999505e-01    <NA>  100
#> 247 18  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  100
#> 248 18  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  100
#> 249 18  1     0 Inf          clast.pred 2.005679e-04    <NA>  100
#> 250 18  1     0 Inf           half.life 8.417051e+00    <NA>  100
#> 251 18  1     0 Inf          span.ratio 1.425677e+01    <NA>  100
#> 252 18  1     0 Inf          aucinf.obs 3.850425e+03    <NA>  100
#> 253 19  1     0  24             auclast 7.000260e+03    <NA>  200
#> 254 19  1     0 Inf                cmax 2.324836e+03    <NA>  200
#> 255 19  1     0 Inf                tmax 1.000000e+00    <NA>  200
#> 256 19  1     0 Inf               tlast 9.600000e+01    <NA>  200
#> 257 19  1     0 Inf           clast.obs 3.000000e-03    <NA>  200
#> 258 19  1     0 Inf            lambda.z 1.058481e-01    <NA>  200
#> 259 19  1     0 Inf           r.squared 9.998804e-01    <NA>  200
#> 260 19  1     0 Inf       adj.r.squared 9.998206e-01    <NA>  200
#> 261 19  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  200
#> 262 19  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  200
#> 263 19  1     0 Inf          clast.pred 2.899822e-03    <NA>  200
#> 264 19  1     0 Inf           half.life 6.548506e+00    <NA>  200
#> 265 19  1     0 Inf          span.ratio 1.099487e+01    <NA>  200
#> 266 19  1     0 Inf          aucinf.obs 7.056708e+03    <NA>  200
#> 267 20  1     0  24             auclast 6.776600e+03    <NA>  200
#> 268 20  1     0 Inf                cmax 2.091633e+03    <NA>  200
#> 269 20  1     0 Inf                tmax 1.000000e+00    <NA>  200
#> 270 20  1     0 Inf               tlast 1.440000e+02    <NA>  200
#> 271 20  1     0 Inf           clast.obs 2.000000e-04    <NA>  200
#> 272 20  1     0 Inf            lambda.z 8.659533e-02    <NA>  200
#> 273 20  1     0 Inf           r.squared 9.999406e-01    <NA>  200
#> 274 20  1     0 Inf       adj.r.squared 9.999208e-01    <NA>  200
#> 275 20  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  200
#> 276 20  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  200
#> 277 20  1     0 Inf          clast.pred 2.046620e-04    <NA>  200
#> 278 20  1     0 Inf           half.life 8.004441e+00    <NA>  200
#> 279 20  1     0 Inf          span.ratio 1.499168e+01    <NA>  200
#> 280 20  1     0 Inf          aucinf.obs 6.852957e+03    <NA>  200
#> 281 21  1     0  24             auclast 5.445269e+03    <NA>  200
#> 282 21  1     0 Inf                cmax 1.785409e+03    <NA>  200
#> 283 21  1     0 Inf                tmax 1.000000e+00    <NA>  200
#> 284 21  1     0 Inf               tlast 1.440000e+02    <NA>  200
#> 285 21  1     0 Inf           clast.obs 2.000000e-04    <NA>  200
#> 286 21  1     0 Inf            lambda.z 8.339245e-02    <NA>  200
#> 287 21  1     0 Inf           r.squared 9.996346e-01    <NA>  200
#> 288 21  1     0 Inf       adj.r.squared 9.995128e-01    <NA>  200
#> 289 21  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  200
#> 290 21  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  200
#> 291 21  1     0 Inf          clast.pred 1.861553e-04    <NA>  200
#> 292 21  1     0 Inf           half.life 8.311870e+00    <NA>  200
#> 293 21  1     0 Inf          span.ratio 1.443718e+01    <NA>  200
#> 294 21  1     0 Inf          aucinf.obs 5.496143e+03    <NA>  200
#> 295 22  1     0  24             auclast 1.583959e+04    <NA>  500
#> 296 22  1     0 Inf                cmax 5.501999e+03    <NA>  500
#> 297 22  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 298 22  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 299 22  1     0 Inf           clast.obs 1.000000e-04    <NA>  500
#> 300 22  1     0 Inf            lambda.z 9.853742e-02    <NA>  500
#> 301 22  1     0 Inf           r.squared 9.998231e-01    <NA>  500
#> 302 22  1     0 Inf       adj.r.squared 9.997642e-01    <NA>  500
#> 303 22  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 304 22  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 305 22  1     0 Inf          clast.pred 9.413641e-05    <NA>  500
#> 306 22  1     0 Inf           half.life 7.034355e+00    <NA>  500
#> 307 22  1     0 Inf          span.ratio 1.705913e+01    <NA>  500
#> 308 22  1     0 Inf          aucinf.obs 1.597458e+04    <NA>  500
#> 309 23  1     0  24             auclast 1.234033e+04    <NA>  500
#> 310 23  1     0 Inf                cmax 4.137234e+03    <NA>  500
#> 311 23  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 312 23  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 313 23  1     0 Inf           clast.obs 1.000000e-04    <NA>  500
#> 314 23  1     0 Inf            lambda.z 9.462305e-02    <NA>  500
#> 315 23  1     0 Inf           r.squared 9.999486e-01    <NA>  500
#> 316 23  1     0 Inf       adj.r.squared 9.999315e-01    <NA>  500
#> 317 23  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 318 23  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 319 23  1     0 Inf          clast.pred 1.014497e-04    <NA>  500
#> 320 23  1     0 Inf           half.life 7.325352e+00    <NA>  500
#> 321 23  1     0 Inf          span.ratio 1.638147e+01    <NA>  500
#> 322 23  1     0 Inf          aucinf.obs 1.243185e+04    <NA>  500
#> 323 24  1     0  24             auclast 2.704707e+04    <NA>  500
#> 324 24  1     0 Inf                cmax 8.426502e+03    <NA>  500
#> 325 24  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 326 24  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 327 24  1     0 Inf           clast.obs 4.000000e-04    <NA>  500
#> 328 24  1     0 Inf            lambda.z 9.501933e-02    <NA>  500
#> 329 24  1     0 Inf           r.squared 9.998974e-01    <NA>  500
#> 330 24  1     0 Inf       adj.r.squared 9.998769e-01    <NA>  500
#> 331 24  1     0 Inf lambda.z.time.first 1.000000e+01    <NA>  500
#> 332 24  1     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 333 24  1     0 Inf          clast.pred 4.038177e-04    <NA>  500
#> 334 24  1     0 Inf           half.life 7.294802e+00    <NA>  500
#> 335 24  1     0 Inf          span.ratio 1.836924e+01    <NA>  500
#> 336 24  1     0 Inf          aucinf.obs 2.740676e+04    <NA>  500
#> 337 25  1     0  24             auclast 1.446619e+04    <NA>  500
#> 338 25  1     0 Inf                cmax 4.607995e+03    <NA>  500
#> 339 25  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 340 25  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 341 25  1     0 Inf           clast.obs 1.000000e-04    <NA>  500
#> 342 25  1     0 Inf            lambda.z 9.628048e-02    <NA>  500
#> 343 25  1     0 Inf           r.squared 9.995134e-01    <NA>  500
#> 344 25  1     0 Inf       adj.r.squared 9.993512e-01    <NA>  500
#> 345 25  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 346 25  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 347 25  1     0 Inf          clast.pred 1.105801e-04    <NA>  500
#> 348 25  1     0 Inf           half.life 7.199249e+00    <NA>  500
#> 349 25  1     0 Inf          span.ratio 1.666841e+01    <NA>  500
#> 350 25  1     0 Inf          aucinf.obs 1.458032e+04    <NA>  500
#> 351 26  1     0  24             auclast 1.354819e+04    <NA>  500
#> 352 26  1     0 Inf                cmax 4.390954e+03    <NA>  500
#> 353 26  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 354 26  1     0 Inf               tlast 9.600000e+01    <NA>  500
#> 355 26  1     0 Inf           clast.obs 4.500000e-03    <NA>  500
#> 356 26  1     0 Inf            lambda.z 1.056342e-01    <NA>  500
#> 357 26  1     0 Inf           r.squared 9.999958e-01    <NA>  500
#> 358 26  1     0 Inf       adj.r.squared 9.999916e-01    <NA>  500
#> 359 26  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 360 26  1     0 Inf   lambda.z.n.points 3.000000e+00    <NA>  500
#> 361 26  1     0 Inf          clast.pred 4.513525e-03    <NA>  500
#> 362 26  1     0 Inf           half.life 6.561770e+00    <NA>  500
#> 363 26  1     0 Inf          span.ratio 7.315099e+00    <NA>  500
#> 364 26  1     0 Inf          aucinf.obs 1.364245e+04    <NA>  500
#> 365 27  1     0  24             auclast 1.061977e+04    <NA>  500
#> 366 27  1     0 Inf                cmax 3.752019e+03    <NA>  500
#> 367 27  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 368 27  1     0 Inf               tlast 9.600000e+01    <NA>  500
#> 369 27  1     0 Inf           clast.obs 4.500000e-03    <NA>  500
#> 370 27  1     0 Inf            lambda.z 1.033160e-01    <NA>  500
#> 371 27  1     0 Inf           r.squared 9.999966e-01    <NA>  500
#> 372 27  1     0 Inf       adj.r.squared 9.999948e-01    <NA>  500
#> 373 27  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 374 27  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  500
#> 375 27  1     0 Inf          clast.pred 4.516459e-03    <NA>  500
#> 376 27  1     0 Inf           half.life 6.708999e+00    <NA>  500
#> 377 27  1     0 Inf          span.ratio 1.073185e+01    <NA>  500
#> 378 27  1     0 Inf          aucinf.obs 1.069405e+04    <NA>  500
#> 379 28  1     0  24             auclast 2.250367e+04    <NA>  800
#> 380 28  1     0 Inf                cmax 7.479920e+03    <NA>  800
#> 381 28  1     0 Inf                tmax 1.000000e+00    <NA>  800
#> 382 28  1     0 Inf               tlast 1.680000e+02    <NA>  800
#> 383 28  1     0 Inf           clast.obs 1.000000e-04    <NA>  800
#> 384 28  1     0 Inf            lambda.z 8.305962e-02    <NA>  800
#> 385 28  1     0 Inf           r.squared 9.996882e-01    <NA>  800
#> 386 28  1     0 Inf       adj.r.squared 9.996102e-01    <NA>  800
#> 387 28  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  800
#> 388 28  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  800
#> 389 28  1     0 Inf          clast.pred 8.894987e-05    <NA>  800
#> 390 28  1     0 Inf           half.life 8.345176e+00    <NA>  800
#> 391 28  1     0 Inf          span.ratio 1.725548e+01    <NA>  800
#> 392 28  1     0 Inf          aucinf.obs 2.267750e+04    <NA>  800
#> 393 29  1     0  24             auclast 1.863645e+04    <NA>  800
#> 394 29  1     0 Inf                cmax 6.486925e+03    <NA>  800
#> 395 29  1     0 Inf                tmax 1.000000e+00    <NA>  800
#> 396 29  1     0 Inf               tlast 1.440000e+02    <NA>  800
#> 397 29  1     0 Inf           clast.obs 1.000000e-04    <NA>  800
#> 398 29  1     0 Inf            lambda.z 9.846170e-02    <NA>  800
#> 399 29  1     0 Inf           r.squared 9.996907e-01    <NA>  800
#> 400 29  1     0 Inf       adj.r.squared 9.995876e-01    <NA>  800
#> 401 29  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  800
#> 402 29  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  800
#> 403 29  1     0 Inf          clast.pred 9.210014e-05    <NA>  800
#> 404 29  1     0 Inf           half.life 7.039764e+00    <NA>  800
#> 405 29  1     0 Inf          span.ratio 1.704603e+01    <NA>  800
#> 406 29  1     0 Inf          aucinf.obs 1.876833e+04    <NA>  800
#> 407 30  1     0  24             auclast 3.002218e+04    <NA>  800
#> 408 30  1     0 Inf                cmax 8.334664e+03    <NA>  800
#> 409 30  1     0 Inf                tmax 1.500000e+00    <NA>  800
#> 410 30  1     0 Inf               tlast 1.440000e+02    <NA>  800
#> 411 30  1     0 Inf           clast.obs 3.000000e-04    <NA>  800
#> 412 30  1     0 Inf            lambda.z 9.567977e-02    <NA>  800
#> 413 30  1     0 Inf           r.squared 9.999637e-01    <NA>  800
#> 414 30  1     0 Inf       adj.r.squared 9.999517e-01    <NA>  800
#> 415 30  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  800
#> 416 30  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  800
#> 417 30  1     0 Inf          clast.pred 2.930591e-04    <NA>  800
#> 418 30  1     0 Inf           half.life 7.244449e+00    <NA>  800
#> 419 30  1     0 Inf          span.ratio 1.656441e+01    <NA>  800
#> 420 30  1     0 Inf          aucinf.obs 3.032327e+04    <NA>  800
#> 421 31  1     0  24             auclast 3.392579e+04    <NA>  800
#> 422 31  1     0 Inf                cmax 9.071352e+03    <NA>  800
#> 423 31  1     0 Inf                tmax 1.000000e+00    <NA>  800
#> 424 31  1     0 Inf               tlast 1.440000e+02    <NA>  800
#> 425 31  1     0 Inf           clast.obs 1.000000e-04    <NA>  800
#> 426 31  1     0 Inf            lambda.z 1.066895e-01    <NA>  800
#> 427 31  1     0 Inf           r.squared 9.999219e-01    <NA>  800
#> 428 31  1     0 Inf       adj.r.squared 9.998959e-01    <NA>  800
#> 429 31  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  800
#> 430 31  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  800
#> 431 31  1     0 Inf          clast.pred 1.045572e-04    <NA>  800
#> 432 31  1     0 Inf           half.life 6.496867e+00    <NA>  800
#> 433 31  1     0 Inf          span.ratio 1.847044e+01    <NA>  800
#> 434 31  1     0 Inf          aucinf.obs 3.427425e+04    <NA>  800
#> 435 32  1     0  24             auclast 1.871379e+04    <NA>  800
#> 436 32  1     0 Inf                cmax 6.288157e+03    <NA>  800
#> 437 32  1     0 Inf                tmax 1.000000e+00    <NA>  800
#> 438 32  1     0 Inf               tlast 1.440000e+02    <NA>  800
#> 439 32  1     0 Inf           clast.obs 2.000000e-04    <NA>  800
#> 440 32  1     0 Inf            lambda.z 9.384124e-02    <NA>  800
#> 441 32  1     0 Inf           r.squared 9.999033e-01    <NA>  800
#> 442 32  1     0 Inf       adj.r.squared 9.998791e-01    <NA>  800
#> 443 32  1     0 Inf lambda.z.time.first 1.200000e+01    <NA>  800
#> 444 32  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  800
#> 445 32  1     0 Inf          clast.pred 2.045114e-04    <NA>  800
#> 446 32  1     0 Inf           half.life 7.386381e+00    <NA>  800
#> 447 32  1     0 Inf          span.ratio 1.787073e+01    <NA>  800
#> 448 32  1     0 Inf          aucinf.obs 1.887601e+04    <NA>  800
#> 449 33  1     0  24             auclast 1.973778e+04    <NA>  800
#> 450 33  1     0 Inf                cmax 6.011806e+03    <NA>  800
#> 451 33  1     0 Inf                tmax 1.000000e+00    <NA>  800
#> 452 33  1     0 Inf               tlast 9.600000e+01    <NA>  800
#> 453 33  1     0 Inf           clast.obs 4.000000e-03    <NA>  800
#> 454 33  1     0 Inf            lambda.z 1.133840e-01    <NA>  800
#> 455 33  1     0 Inf           r.squared 9.999439e-01    <NA>  800
#> 456 33  1     0 Inf       adj.r.squared 9.999158e-01    <NA>  800
#> 457 33  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  800
#> 458 33  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  800
#> 459 33  1     0 Inf          clast.pred 4.091777e-03    <NA>  800
#> 460 33  1     0 Inf           half.life 6.113271e+00    <NA>  800
#> 461 33  1     0 Inf          span.ratio 1.177766e+01    <NA>  800
#> 462 33  1     0 Inf          aucinf.obs 1.986365e+04    <NA>  800
#> 463 34  1     0  24             auclast 2.232290e+04    <NA> 1000
#> 464 34  1     0 Inf                cmax 7.332282e+03    <NA> 1000
#> 465 34  1     0 Inf                tmax 1.000000e+00    <NA> 1000
#> 466 34  1     0 Inf               tlast 1.440000e+02    <NA> 1000
#> 467 34  1     0 Inf           clast.obs 1.000000e-04    <NA> 1000
#> 468 34  1     0 Inf            lambda.z 9.914251e-02    <NA> 1000
#> 469 34  1     0 Inf           r.squared 9.999461e-01    <NA> 1000
#> 470 34  1     0 Inf       adj.r.squared 9.998922e-01    <NA> 1000
#> 471 34  1     0 Inf lambda.z.time.first 7.200000e+01    <NA> 1000
#> 472 34  1     0 Inf   lambda.z.n.points 3.000000e+00    <NA> 1000
#> 473 34  1     0 Inf          clast.pred 9.899653e-05    <NA> 1000
#> 474 34  1     0 Inf           half.life 6.991423e+00    <NA> 1000
#> 475 34  1     0 Inf          span.ratio 1.029833e+01    <NA> 1000
#> 476 34  1     0 Inf          aucinf.obs 2.250714e+04    <NA> 1000
#> 477 35  1     0  24             auclast 3.252422e+04    <NA> 1000
#> 478 35  1     0 Inf                cmax 1.073462e+04    <NA> 1000
#> 479 35  1     0 Inf                tmax 1.000000e+00    <NA> 1000
#> 480 35  1     0 Inf               tlast 1.440000e+02    <NA> 1000
#> 481 35  1     0 Inf           clast.obs 3.000000e-04    <NA> 1000
#> 482 35  1     0 Inf            lambda.z 9.555373e-02    <NA> 1000
#> 483 35  1     0 Inf           r.squared 9.999367e-01    <NA> 1000
#> 484 35  1     0 Inf       adj.r.squared 9.999209e-01    <NA> 1000
#> 485 35  1     0 Inf lambda.z.time.first 1.200000e+01    <NA> 1000
#> 486 35  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA> 1000
#> 487 35  1     0 Inf          clast.pred 3.004602e-04    <NA> 1000
#> 488 35  1     0 Inf           half.life 7.254004e+00    <NA> 1000
#> 489 35  1     0 Inf          span.ratio 1.819685e+01    <NA> 1000
#> 490 35  1     0 Inf          aucinf.obs 3.281589e+04    <NA> 1000
#> 491 36  1     0  24             auclast 3.787009e+04    <NA> 1000
#> 492 36  1     0 Inf                cmax 1.177701e+04    <NA> 1000
#> 493 36  1     0 Inf                tmax 1.000000e+00    <NA> 1000
#> 494 36  1     0 Inf               tlast 1.680000e+02    <NA> 1000
#> 495 36  1     0 Inf           clast.obs 1.000000e-04    <NA> 1000
#> 496 36  1     0 Inf            lambda.z 8.923816e-02    <NA> 1000
#> 497 36  1     0 Inf           r.squared 9.987622e-01    <NA> 1000
#> 498 36  1     0 Inf       adj.r.squared 9.984528e-01    <NA> 1000
#> 499 36  1     0 Inf lambda.z.time.first 2.400000e+01    <NA> 1000
#> 500 36  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA> 1000
#> 501 36  1     0 Inf          clast.pred 7.708138e-05    <NA> 1000
#> 502 36  1     0 Inf           half.life 7.767385e+00    <NA> 1000
#> 503 36  1     0 Inf          span.ratio 1.853906e+01    <NA> 1000
#> 504 36  1     0 Inf          aucinf.obs 3.821574e+04    <NA> 1000
#> 505 37  1     0  24             auclast 1.842380e+04    <NA>  500
#> 506 37  1     0 Inf                cmax 6.388314e+03    <NA>  500
#> 507 37  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 508 37  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 509 37  1     0 Inf           clast.obs 4.000000e-04    <NA>  500
#> 510 37  1     0 Inf            lambda.z 8.832400e-02    <NA>  500
#> 511 37  1     0 Inf           r.squared 9.999527e-01    <NA>  500
#> 512 37  1     0 Inf       adj.r.squared 9.999369e-01    <NA>  500
#> 513 37  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 514 37  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 515 37  1     0 Inf          clast.pred 3.909153e-04    <NA>  500
#> 516 37  1     0 Inf           half.life 7.847779e+00    <NA>  500
#> 517 37  1     0 Inf          span.ratio 1.529095e+01    <NA>  500
#> 518 37  1     0 Inf          aucinf.obs 1.860268e+04    <NA>  500
#> 519 38  1     0  24             auclast 1.401704e+04    <NA>  500
#> 520 38  1     0 Inf                cmax 4.814671e+03    <NA>  500
#> 521 38  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 522 38  1     0 Inf               tlast 9.600000e+01    <NA>  500
#> 523 38  1     0 Inf           clast.obs 5.600000e-03    <NA>  500
#> 524 38  1     0 Inf            lambda.z 1.036302e-01    <NA>  500
#> 525 38  1     0 Inf           r.squared 9.999967e-01    <NA>  500
#> 526 38  1     0 Inf       adj.r.squared 9.999951e-01    <NA>  500
#> 527 38  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 528 38  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  500
#> 529 38  1     0 Inf          clast.pred 5.622718e-03    <NA>  500
#> 530 38  1     0 Inf           half.life 6.688663e+00    <NA>  500
#> 531 38  1     0 Inf          span.ratio 1.076448e+01    <NA>  500
#> 532 38  1     0 Inf          aucinf.obs 1.411132e+04    <NA>  500
#> 533 39  1     0  24             auclast 9.911626e+03    <NA>  500
#> 534 39  1     0 Inf                cmax 3.553992e+03    <NA>  500
#> 535 39  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 536 39  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 537 39  1     0 Inf           clast.obs 2.000000e-04    <NA>  500
#> 538 39  1     0 Inf            lambda.z 8.642586e-02    <NA>  500
#> 539 39  1     0 Inf           r.squared 9.999689e-01    <NA>  500
#> 540 39  1     0 Inf       adj.r.squared 9.999585e-01    <NA>  500
#> 541 39  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 542 39  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 543 39  1     0 Inf          clast.pred 1.965897e-04    <NA>  500
#> 544 39  1     0 Inf           half.life 8.020136e+00    <NA>  500
#> 545 39  1     0 Inf          span.ratio 1.496234e+01    <NA>  500
#> 546 39  1     0 Inf          aucinf.obs 9.984762e+03    <NA>  500
#> 547 40  1     0  24             auclast 2.110296e+04    <NA>  500
#> 548 40  1     0 Inf                cmax 6.406481e+03    <NA>  500
#> 549 40  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 550 40  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 551 40  1     0 Inf           clast.obs 4.000000e-04    <NA>  500
#> 552 40  1     0 Inf            lambda.z 9.135775e-02    <NA>  500
#> 553 40  1     0 Inf           r.squared 9.999753e-01    <NA>  500
#> 554 40  1     0 Inf       adj.r.squared 9.999670e-01    <NA>  500
#> 555 40  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 556 40  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 557 40  1     0 Inf          clast.pred 3.988927e-04    <NA>  500
#> 558 40  1     0 Inf           half.life 7.587174e+00    <NA>  500
#> 559 40  1     0 Inf          span.ratio 1.581616e+01    <NA>  500
#> 560 40  1     0 Inf          aucinf.obs 2.135506e+04    <NA>  500
#> 561 41  1     0  24             auclast 9.606489e+03    <NA>  500
#> 562 41  1     0 Inf                cmax 3.378997e+03    <NA>  500
#> 563 41  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 564 41  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 565 41  1     0 Inf           clast.obs 2.000000e-04    <NA>  500
#> 566 41  1     0 Inf            lambda.z 8.596185e-02    <NA>  500
#> 567 41  1     0 Inf           r.squared 9.998521e-01    <NA>  500
#> 568 41  1     0 Inf       adj.r.squared 9.998029e-01    <NA>  500
#> 569 41  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 570 41  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 571 41  1     0 Inf          clast.pred 2.099408e-04    <NA>  500
#> 572 41  1     0 Inf           half.life 8.063428e+00    <NA>  500
#> 573 41  1     0 Inf          span.ratio 1.488201e+01    <NA>  500
#> 574 41  1     0 Inf          aucinf.obs 9.678709e+03    <NA>  500
#> 575 42  1     0  24             auclast 1.080272e+04    <NA>  500
#> 576 42  1     0 Inf                cmax 3.596331e+03    <NA>  500
#> 577 42  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 578 42  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 579 42  1     0 Inf           clast.obs 1.000000e-04    <NA>  500
#> 580 42  1     0 Inf            lambda.z 7.966875e-02    <NA>  500
#> 581 42  1     0 Inf           r.squared 9.983950e-01    <NA>  500
#> 582 42  1     0 Inf       adj.r.squared 9.979938e-01    <NA>  500
#> 583 42  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 584 42  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 585 42  1     0 Inf          clast.pred 7.642016e-05    <NA>  500
#> 586 42  1     0 Inf           half.life 8.700365e+00    <NA>  500
#> 587 42  1     0 Inf          span.ratio 1.655103e+01    <NA>  500
#> 588 42  1     0 Inf          aucinf.obs 1.090034e+04    <NA>  500
#> 589 43  1     0  24             auclast 2.159418e+04    <NA>  500
#> 590 43  1     0 Inf                cmax 5.899466e+03    <NA>  500
#> 591 43  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 592 43  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 593 43  1     0 Inf           clast.obs 1.000000e-04    <NA>  500
#> 594 43  1     0 Inf            lambda.z 1.038920e-01    <NA>  500
#> 595 43  1     0 Inf           r.squared 9.992929e-01    <NA>  500
#> 596 43  1     0 Inf       adj.r.squared 9.990571e-01    <NA>  500
#> 597 43  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 598 43  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 599 43  1     0 Inf          clast.pred 8.760502e-05    <NA>  500
#> 600 43  1     0 Inf           half.life 6.671806e+00    <NA>  500
#> 601 43  1     0 Inf          span.ratio 1.798614e+01    <NA>  500
#> 602 43  1     0 Inf          aucinf.obs 2.182821e+04    <NA>  500
#> 603 44  1     0  24             auclast 2.414661e+04    <NA>  500
#> 604 44  1     0 Inf                cmax 7.981871e+03    <NA>  500
#> 605 44  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 606 44  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 607 44  1     0 Inf           clast.obs 2.000000e-04    <NA>  500
#> 608 44  1     0 Inf            lambda.z 8.066645e-02    <NA>  500
#> 609 44  1     0 Inf           r.squared 9.998778e-01    <NA>  500
#> 610 44  1     0 Inf       adj.r.squared 9.998534e-01    <NA>  500
#> 611 44  1     0 Inf lambda.z.time.first 1.200000e+01    <NA>  500
#> 612 44  1     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 613 44  1     0 Inf          clast.pred 2.105656e-04    <NA>  500
#> 614 44  1     0 Inf           half.life 8.592756e+00    <NA>  500
#> 615 44  1     0 Inf          span.ratio 1.815483e+01    <NA>  500
#> 616 44  1     0 Inf          aucinf.obs 2.442868e+04    <NA>  500
#> 617 45  1     0  24             auclast 1.709256e+04    <NA>  500
#> 618 45  1     0 Inf                cmax 5.031265e+03    <NA>  500
#> 619 45  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 620 45  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 621 45  1     0 Inf           clast.obs 2.000000e-04    <NA>  500
#> 622 45  1     0 Inf            lambda.z 9.431686e-02    <NA>  500
#> 623 45  1     0 Inf           r.squared 9.999652e-01    <NA>  500
#> 624 45  1     0 Inf       adj.r.squared 9.999536e-01    <NA>  500
#> 625 45  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 626 45  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 627 45  1     0 Inf          clast.pred 1.950136e-04    <NA>  500
#> 628 45  1     0 Inf           half.life 7.349133e+00    <NA>  500
#> 629 45  1     0 Inf          span.ratio 1.632846e+01    <NA>  500
#> 630 45  1     0 Inf          aucinf.obs 1.726502e+04    <NA>  500
#> 631 46  1     0  24             auclast 1.174430e+04    <NA>  500
#> 632 46  1     0 Inf                cmax 3.940205e+03    <NA>  500
#> 633 46  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 634 46  1     0 Inf               tlast 9.600000e+01    <NA>  500
#> 635 46  1     0 Inf           clast.obs 6.000000e-04    <NA>  500
#> 636 46  1     0 Inf            lambda.z 1.308467e-01    <NA>  500
#> 637 46  1     0 Inf           r.squared 9.999813e-01    <NA>  500
#> 638 46  1     0 Inf       adj.r.squared 9.999719e-01    <NA>  500
#> 639 46  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 640 46  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  500
#> 641 46  1     0 Inf          clast.pred 5.936901e-04    <NA>  500
#> 642 46  1     0 Inf           half.life 5.297400e+00    <NA>  500
#> 643 46  1     0 Inf          span.ratio 1.359157e+01    <NA>  500
#> 644 46  1     0 Inf          aucinf.obs 1.180045e+04    <NA>  500
#> 645 47  1     0  24             auclast 1.781765e+04    <NA>  500
#> 646 47  1     0 Inf                cmax 6.210117e+03    <NA>  500
#> 647 47  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 648 47  1     0 Inf               tlast 1.440000e+02    <NA>  500
#> 649 47  1     0 Inf           clast.obs 2.000000e-04    <NA>  500
#> 650 47  1     0 Inf            lambda.z 9.309795e-02    <NA>  500
#> 651 47  1     0 Inf           r.squared 9.999411e-01    <NA>  500
#> 652 47  1     0 Inf       adj.r.squared 9.999214e-01    <NA>  500
#> 653 47  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 654 47  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 655 47  1     0 Inf          clast.pred 2.056943e-04    <NA>  500
#> 656 47  1     0 Inf           half.life 7.445354e+00    <NA>  500
#> 657 47  1     0 Inf          span.ratio 1.611743e+01    <NA>  500
#> 658 47  1     0 Inf          aucinf.obs 1.797211e+04    <NA>  500
#> 659 48  1     0  24             auclast 1.199247e+04    <NA>  500
#> 660 48  1     0 Inf                cmax 3.793325e+03    <NA>  500
#> 661 48  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 662 48  1     0 Inf               tlast 9.600000e+01    <NA>  500
#> 663 48  1     0 Inf           clast.obs 3.200000e-03    <NA>  500
#> 664 48  1     0 Inf            lambda.z 1.103228e-01    <NA>  500
#> 665 48  1     0 Inf           r.squared 9.998781e-01    <NA>  500
#> 666 48  1     0 Inf       adj.r.squared 9.998171e-01    <NA>  500
#> 667 48  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 668 48  1     0 Inf   lambda.z.n.points 4.000000e+00    <NA>  500
#> 669 48  1     0 Inf          clast.pred 3.233494e-03    <NA>  500
#> 670 48  1     0 Inf           half.life 6.282898e+00    <NA>  500
#> 671 48  1     0 Inf          span.ratio 1.145968e+01    <NA>  500
#> 672 48  1     0 Inf          aucinf.obs 1.207482e+04    <NA>  500
nca1(examplinib_fe_nif, time = "TAD", group = "FASTED")
#> NCA: No analyte specified. Selected RS2023 as the most likely.
#> NCA: Group by FASTED
#> Warning: Negative concentrations found
#>     FASTED ID DI start end            PPTESTCD      PPORRES exclude DOSE
#> 1        1  1  1     0  24             auclast 2.504642e+04    <NA>  500
#> 2        1  1  1     0 Inf                cmax 6.325101e+03    <NA>  500
#> 3        1  1  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 4        1  1  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 5        1  1  1     0 Inf           clast.obs 9.704193e-05    <NA>  500
#> 6        1  1  1     0 Inf            lambda.z 8.895551e-02    <NA>  500
#> 7        1  1  1     0 Inf           r.squared 9.999811e-01    <NA>  500
#> 8        1  1  1     0 Inf       adj.r.squared 9.999764e-01    <NA>  500
#> 9        1  1  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 10       1  1  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 11       1  1  1     0 Inf          clast.pred 9.649364e-05    <NA>  500
#> 12       1  1  1     0 Inf           half.life 7.792066e+00    <NA>  500
#> 13       1  1  1     0 Inf          span.ratio 1.848034e+01    <NA>  500
#> 14       1  1  1     0 Inf          aucinf.obs 2.544210e+04    <NA>  500
#> 15       0  1  2     0  24             auclast 3.431709e+04    <NA>  500
#> 16       0  1  2     0 Inf                cmax 4.956902e+03    <NA>  500
#> 17       0  1  2     0 Inf                tmax 3.000000e+00    <NA>  500
#> 18       0  1  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 19       0  1  2     0 Inf           clast.obs 1.845688e-04    <NA>  500
#> 20       0  1  2     0 Inf            lambda.z 8.884753e-02    <NA>  500
#> 21       0  1  2     0 Inf           r.squared 9.999968e-01    <NA>  500
#> 22       0  1  2     0 Inf       adj.r.squared 9.999958e-01    <NA>  500
#> 23       0  1  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 24       0  1  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 25       0  1  2     0 Inf          clast.pred 1.853255e-04    <NA>  500
#> 26       0  1  2     0 Inf           half.life 7.801536e+00    <NA>  500
#> 27       0  1  2     0 Inf          span.ratio 1.538159e+01    <NA>  500
#> 28       0  1  2     0 Inf          aucinf.obs 3.521725e+04    <NA>  500
#> 29       0  2  1     0  24             auclast 1.787013e+04    <NA>  500
#> 30       0  2  1     0 Inf                cmax 2.789380e+03    <NA>  500
#> 31       0  2  1     0 Inf                tmax 2.000000e+00    <NA>  500
#> 32       0  2  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 33       0  2  1     0 Inf           clast.obs 4.580125e-05    <NA>  500
#> 34       0  2  1     0 Inf            lambda.z 9.187966e-02    <NA>  500
#> 35       0  2  1     0 Inf           r.squared 9.999718e-01    <NA>  500
#> 36       0  2  1     0 Inf       adj.r.squared 9.999624e-01    <NA>  500
#> 37       0  2  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 38       0  2  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 39       0  2  1     0 Inf          clast.pred 4.548237e-05    <NA>  500
#> 40       0  2  1     0 Inf           half.life 7.544077e+00    <NA>  500
#> 41       0  2  1     0 Inf          span.ratio 1.590652e+01    <NA>  500
#> 42       0  2  1     0 Inf          aucinf.obs 1.825264e+04    <NA>  500
#> 43       1  2  2     0  24             auclast 1.178450e+04    <NA>  500
#> 44       1  2  2     0 Inf                cmax 3.431745e+03    <NA>  500
#> 45       1  2  2     0 Inf                tmax 1.000000e+00    <NA>  500
#> 46       1  2  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 47       1  2  2     0 Inf           clast.obs 2.193043e-05    <NA>  500
#> 48       1  2  2     0 Inf            lambda.z 9.165476e-02    <NA>  500
#> 49       1  2  2     0 Inf           r.squared 9.999814e-01    <NA>  500
#> 50       1  2  2     0 Inf       adj.r.squared 9.999768e-01    <NA>  500
#> 51       1  2  2     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 52       1  2  2     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 53       1  2  2     0 Inf          clast.pred 2.148559e-05    <NA>  500
#> 54       1  2  2     0 Inf           half.life 7.562588e+00    <NA>  500
#> 55       1  2  2     0 Inf          span.ratio 1.904110e+01    <NA>  500
#> 56       1  2  2     0 Inf          aucinf.obs 1.191081e+04    <NA>  500
#> 57       1  3  1     0  24             auclast 2.127273e+04    <NA>  500
#> 58       1  3  1     0 Inf                cmax 6.439872e+03    <NA>  500
#> 59       1  3  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 60       1  3  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 61       1  3  1     0 Inf           clast.obs 7.390936e-06    <NA>  500
#> 62       1  3  1     0 Inf            lambda.z 1.047673e-01    <NA>  500
#> 63       1  3  1     0 Inf           r.squared 9.999660e-01    <NA>  500
#> 64       1  3  1     0 Inf       adj.r.squared 9.999592e-01    <NA>  500
#> 65       1  3  1     0 Inf lambda.z.time.first 1.200000e+01    <NA>  500
#> 66       1  3  1     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 67       1  3  1     0 Inf          clast.pred 7.106165e-06    <NA>  500
#> 68       1  3  1     0 Inf           half.life 6.616064e+00    <NA>  500
#> 69       1  3  1     0 Inf          span.ratio 2.357897e+01    <NA>  500
#> 70       1  3  1     0 Inf          aucinf.obs 2.150811e+04    <NA>  500
#> 71       0  3  2     0  24             auclast 3.058559e+04    <NA>  500
#> 72       0  3  2     0 Inf                cmax 4.767907e+03    <NA>  500
#> 73       0  3  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 74       0  3  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 75       0  3  2     0 Inf           clast.obs 1.462743e-05    <NA>  500
#> 76       0  3  2     0 Inf            lambda.z 1.045455e-01    <NA>  500
#> 77       0  3  2     0 Inf           r.squared 9.999830e-01    <NA>  500
#> 78       0  3  2     0 Inf       adj.r.squared 9.999773e-01    <NA>  500
#> 79       0  3  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 80       0  3  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 81       0  3  2     0 Inf          clast.pred 1.458709e-05    <NA>  500
#> 82       0  3  2     0 Inf           half.life 6.630102e+00    <NA>  500
#> 83       0  3  2     0 Inf          span.ratio 1.809927e+01    <NA>  500
#> 84       0  3  2     0 Inf          aucinf.obs 3.116406e+04    <NA>  500
#> 85       1  4  1     0  24             auclast 2.443897e+04    <NA>  500
#> 86       1  4  1     0 Inf                cmax 6.043145e+03    <NA>  500
#> 87       1  4  1     0 Inf                tmax 1.500000e+00    <NA>  500
#> 88       1  4  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 89       1  4  1     0 Inf           clast.obs 1.984748e-04    <NA>  500
#> 90       1  4  1     0 Inf            lambda.z 8.484051e-02    <NA>  500
#> 91       1  4  1     0 Inf           r.squared 9.999722e-01    <NA>  500
#> 92       1  4  1     0 Inf       adj.r.squared 9.999652e-01    <NA>  500
#> 93       1  4  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 94       1  4  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 95       1  4  1     0 Inf          clast.pred 1.988844e-04    <NA>  500
#> 96       1  4  1     0 Inf           half.life 8.170002e+00    <NA>  500
#> 97       1  4  1     0 Inf          span.ratio 1.762545e+01    <NA>  500
#> 98       1  4  1     0 Inf          aucinf.obs 2.491278e+04    <NA>  500
#> 99       0  4  2     0  24             auclast 3.817864e+04    <NA>  500
#> 100      0  4  2     0 Inf                cmax 5.333942e+03    <NA>  500
#> 101      0  4  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 102      0  4  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 103      0  4  2     0 Inf           clast.obs 3.870134e-04    <NA>  500
#> 104      0  4  2     0 Inf            lambda.z 8.522916e-02    <NA>  500
#> 105      0  4  2     0 Inf           r.squared 9.999328e-01    <NA>  500
#> 106      0  4  2     0 Inf       adj.r.squared 9.999104e-01    <NA>  500
#> 107      0  4  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 108      0  4  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 109      0  4  2     0 Inf          clast.pred 4.005540e-04    <NA>  500
#> 110      0  4  2     0 Inf           half.life 8.132747e+00    <NA>  500
#> 111      0  4  2     0 Inf          span.ratio 1.475516e+01    <NA>  500
#> 112      0  4  2     0 Inf          aucinf.obs 3.934480e+04    <NA>  500
#> 113      0  5  1     0  24             auclast 3.202317e+04    <NA>  500
#> 114      0  5  1     0 Inf                cmax 5.283736e+03    <NA>  500
#> 115      0  5  1     0 Inf                tmax 2.000000e+00    <NA>  500
#> 116      0  5  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 117      0  5  1     0 Inf           clast.obs 3.525085e-05    <NA>  500
#> 118      0  5  1     0 Inf            lambda.z 9.840913e-02    <NA>  500
#> 119      0  5  1     0 Inf           r.squared 9.999789e-01    <NA>  500
#> 120      0  5  1     0 Inf       adj.r.squared 9.999718e-01    <NA>  500
#> 121      0  5  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 122      0  5  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 123      0  5  1     0 Inf          clast.pred 3.514853e-05    <NA>  500
#> 124      0  5  1     0 Inf           half.life 7.043525e+00    <NA>  500
#> 125      0  5  1     0 Inf          span.ratio 1.703692e+01    <NA>  500
#> 126      0  5  1     0 Inf          aucinf.obs 3.262419e+04    <NA>  500
#> 127      1  5  2     0  24             auclast 2.316675e+04    <NA>  500
#> 128      1  5  2     0 Inf                cmax 7.048011e+03    <NA>  500
#> 129      1  5  2     0 Inf                tmax 1.000000e+00    <NA>  500
#> 130      1  5  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 131      1  5  2     0 Inf           clast.obs 1.856992e-05    <NA>  500
#> 132      1  5  2     0 Inf            lambda.z 9.916635e-02    <NA>  500
#> 133      1  5  2     0 Inf           r.squared 9.999721e-01    <NA>  500
#> 134      1  5  2     0 Inf       adj.r.squared 9.999665e-01    <NA>  500
#> 135      1  5  2     0 Inf lambda.z.time.first 1.200000e+01    <NA>  500
#> 136      1  5  2     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 137      1  5  2     0 Inf          clast.pred 1.843892e-05    <NA>  500
#> 138      1  5  2     0 Inf           half.life 6.989742e+00    <NA>  500
#> 139      1  5  2     0 Inf          span.ratio 2.231842e+01    <NA>  500
#> 140      1  5  2     0 Inf          aucinf.obs 2.345301e+04    <NA>  500
#> 141      0  6  1     0  24             auclast 2.563207e+04    <NA>  500
#> 142      0  6  1     0 Inf                cmax 4.106337e+03    <NA>  500
#> 143      0  6  1     0 Inf                tmax 2.000000e+00    <NA>  500
#> 144      0  6  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 145      0  6  1     0 Inf           clast.obs 2.177254e-04    <NA>  500
#> 146      0  6  1     0 Inf            lambda.z 8.351055e-02    <NA>  500
#> 147      0  6  1     0 Inf           r.squared 9.999362e-01    <NA>  500
#> 148      0  6  1     0 Inf       adj.r.squared 9.999149e-01    <NA>  500
#> 149      0  6  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 150      0  6  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 151      0  6  1     0 Inf          clast.pred 2.177732e-04    <NA>  500
#> 152      0  6  1     0 Inf           half.life 8.300115e+00    <NA>  500
#> 153      0  6  1     0 Inf          span.ratio 1.445763e+01    <NA>  500
#> 154      0  6  1     0 Inf          aucinf.obs 2.617468e+04    <NA>  500
#> 155      1  6  2     0  24             auclast 1.899695e+04    <NA>  500
#> 156      1  6  2     0 Inf                cmax 5.739598e+03    <NA>  500
#> 157      1  6  2     0 Inf                tmax 1.000000e+00    <NA>  500
#> 158      1  6  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 159      1  6  2     0 Inf           clast.obs 1.165818e-04    <NA>  500
#> 160      1  6  2     0 Inf            lambda.z 8.317751e-02    <NA>  500
#> 161      1  6  2     0 Inf           r.squared 9.999067e-01    <NA>  500
#> 162      1  6  2     0 Inf       adj.r.squared 9.998833e-01    <NA>  500
#> 163      1  6  2     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 164      1  6  2     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 165      1  6  2     0 Inf          clast.pred 1.225531e-04    <NA>  500
#> 166      1  6  2     0 Inf           half.life 8.333349e+00    <NA>  500
#> 167      1  6  2     0 Inf          span.ratio 1.727997e+01    <NA>  500
#> 168      1  6  2     0 Inf          aucinf.obs 1.922765e+04    <NA>  500
#> 169      0  7  1     0  24             auclast 2.479636e+04    <NA>  500
#> 170      0  7  1     0 Inf                cmax 3.525703e+03    <NA>  500
#> 171      0  7  1     0 Inf                tmax 3.000000e+00    <NA>  500
#> 172      0  7  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 173      0  7  1     0 Inf           clast.obs 2.398994e-05    <NA>  500
#> 174      0  7  1     0 Inf            lambda.z 9.960954e-02    <NA>  500
#> 175      0  7  1     0 Inf           r.squared 9.999575e-01    <NA>  500
#> 176      0  7  1     0 Inf       adj.r.squared 9.999433e-01    <NA>  500
#> 177      0  7  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 178      0  7  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 179      0  7  1     0 Inf          clast.pred 2.430465e-05    <NA>  500
#> 180      0  7  1     0 Inf           half.life 6.958642e+00    <NA>  500
#> 181      0  7  1     0 Inf          span.ratio 1.724474e+01    <NA>  500
#> 182      0  7  1     0 Inf          aucinf.obs 2.536877e+04    <NA>  500
#> 183      1  7  2     0  24             auclast 1.878799e+04    <NA>  500
#> 184      1  7  2     0 Inf                cmax 5.463950e+03    <NA>  500
#> 185      1  7  2     0 Inf                tmax 1.000000e+00    <NA>  500
#> 186      1  7  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 187      1  7  2     0 Inf           clast.obs 1.318929e-05    <NA>  500
#> 188      1  7  2     0 Inf            lambda.z 9.906323e-02    <NA>  500
#> 189      1  7  2     0 Inf           r.squared 9.999512e-01    <NA>  500
#> 190      1  7  2     0 Inf       adj.r.squared 9.999390e-01    <NA>  500
#> 191      1  7  2     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 192      1  7  2     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 193      1  7  2     0 Inf          clast.pred 1.290949e-05    <NA>  500
#> 194      1  7  2     0 Inf           half.life 6.997018e+00    <NA>  500
#> 195      1  7  2     0 Inf          span.ratio 2.058020e+01    <NA>  500
#> 196      1  7  2     0 Inf          aucinf.obs 1.899722e+04    <NA>  500
#> 197      1  8  1     0  24             auclast 2.721779e+04    <NA>  500
#> 198      1  8  1     0 Inf                cmax 6.994537e+03    <NA>  500
#> 199      1  8  1     0 Inf                tmax 1.500000e+00    <NA>  500
#> 200      1  8  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 201      1  8  1     0 Inf           clast.obs 7.224614e-05    <NA>  500
#> 202      1  8  1     0 Inf            lambda.z 9.219047e-02    <NA>  500
#> 203      1  8  1     0 Inf           r.squared 9.999442e-01    <NA>  500
#> 204      1  8  1     0 Inf       adj.r.squared 9.999330e-01    <NA>  500
#> 205      1  8  1     0 Inf lambda.z.time.first 1.200000e+01    <NA>  500
#> 206      1  8  1     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 207      1  8  1     0 Inf          clast.pred 7.169306e-05    <NA>  500
#> 208      1  8  1     0 Inf           half.life 7.518643e+00    <NA>  500
#> 209      1  8  1     0 Inf          span.ratio 2.074843e+01    <NA>  500
#> 210      1  8  1     0 Inf          aucinf.obs 2.765162e+04    <NA>  500
#> 211      0  8  2     0  24             auclast 3.788023e+04    <NA>  500
#> 212      0  8  2     0 Inf                cmax 5.483093e+03    <NA>  500
#> 213      0  8  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 214      0  8  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 215      0  8  2     0 Inf           clast.obs 1.471476e-04    <NA>  500
#> 216      0  8  2     0 Inf            lambda.z 9.125122e-02    <NA>  500
#> 217      0  8  2     0 Inf           r.squared 9.999876e-01    <NA>  500
#> 218      0  8  2     0 Inf       adj.r.squared 9.999835e-01    <NA>  500
#> 219      0  8  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 220      0  8  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 221      0  8  2     0 Inf          clast.pred 1.451554e-04    <NA>  500
#> 222      0  8  2     0 Inf           half.life 7.596032e+00    <NA>  500
#> 223      0  8  2     0 Inf          span.ratio 1.579772e+01    <NA>  500
#> 224      0  8  2     0 Inf          aucinf.obs 3.886029e+04    <NA>  500
#> 225      0  9  1     0  24             auclast 3.965673e+04    <NA>  500
#> 226      0  9  1     0 Inf                cmax 5.496735e+03    <NA>  500
#> 227      0  9  1     0 Inf                tmax 3.000000e+00    <NA>  500
#> 228      0  9  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 229      0  9  1     0 Inf           clast.obs 2.767436e-04    <NA>  500
#> 230      0  9  1     0 Inf            lambda.z 8.765911e-02    <NA>  500
#> 231      0  9  1     0 Inf           r.squared 9.999889e-01    <NA>  500
#> 232      0  9  1     0 Inf       adj.r.squared 9.999852e-01    <NA>  500
#> 233      0  9  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 234      0  9  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 235      0  9  1     0 Inf          clast.pred 2.815239e-04    <NA>  500
#> 236      0  9  1     0 Inf           half.life 7.907304e+00    <NA>  500
#> 237      0  9  1     0 Inf          span.ratio 1.517584e+01    <NA>  500
#> 238      0  9  1     0 Inf          aucinf.obs 4.087872e+04    <NA>  500
#> 239      1  9  2     0  24             auclast 2.903697e+04    <NA>  500
#> 240      1  9  2     0 Inf                cmax 7.358267e+03    <NA>  500
#> 241      1  9  2     0 Inf                tmax 1.500000e+00    <NA>  500
#> 242      1  9  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 243      1  9  2     0 Inf           clast.obs 1.519074e-04    <NA>  500
#> 244      1  9  2     0 Inf            lambda.z 8.781736e-02    <NA>  500
#> 245      1  9  2     0 Inf           r.squared 9.999437e-01    <NA>  500
#> 246      1  9  2     0 Inf       adj.r.squared 9.999297e-01    <NA>  500
#> 247      1  9  2     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 248      1  9  2     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 249      1  9  2     0 Inf          clast.pred 1.437517e-04    <NA>  500
#> 250      1  9  2     0 Inf           half.life 7.893054e+00    <NA>  500
#> 251      1  9  2     0 Inf          span.ratio 1.824389e+01    <NA>  500
#> 252      1  9  2     0 Inf          aucinf.obs 2.955187e+04    <NA>  500
#> 253      0 10  1     0  24             auclast 2.608545e+04    <NA>  500
#> 254      0 10  1     0 Inf                cmax 3.842711e+03    <NA>  500
#> 255      0 10  1     0 Inf                tmax 2.000000e+00    <NA>  500
#> 256      0 10  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 257      0 10  1     0 Inf           clast.obs 2.539811e-04    <NA>  500
#> 258      0 10  1     0 Inf            lambda.z 8.367580e-02    <NA>  500
#> 259      0 10  1     0 Inf           r.squared 9.999242e-01    <NA>  500
#> 260      0 10  1     0 Inf       adj.r.squared 9.998989e-01    <NA>  500
#> 261      0 10  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 262      0 10  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 263      0 10  1     0 Inf          clast.pred 2.446392e-04    <NA>  500
#> 264      0 10  1     0 Inf           half.life 8.283723e+00    <NA>  500
#> 265      0 10  1     0 Inf          span.ratio 1.448624e+01    <NA>  500
#> 266      0 10  1     0 Inf          aucinf.obs 2.675187e+04    <NA>  500
#> 267      1 10  2     0  24             auclast 1.772037e+04    <NA>  500
#> 268      1 10  2     0 Inf                cmax 4.871447e+03    <NA>  500
#> 269      1 10  2     0 Inf                tmax 1.000000e+00    <NA>  500
#> 270      1 10  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 271      1 10  2     0 Inf           clast.obs 1.237101e-04    <NA>  500
#> 272      1 10  2     0 Inf            lambda.z 8.358936e-02    <NA>  500
#> 273      1 10  2     0 Inf           r.squared 9.999874e-01    <NA>  500
#> 274      1 10  2     0 Inf       adj.r.squared 9.999842e-01    <NA>  500
#> 275      1 10  2     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 276      1 10  2     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 277      1 10  2     0 Inf          clast.pred 1.237650e-04    <NA>  500
#> 278      1 10  2     0 Inf           half.life 8.292290e+00    <NA>  500
#> 279      1 10  2     0 Inf          span.ratio 1.736553e+01    <NA>  500
#> 280      1 10  2     0 Inf          aucinf.obs 1.797195e+04    <NA>  500
#> 281      0 11  1     0  24             auclast 2.142685e+04    <NA>  500
#> 282      0 11  1     0 Inf                cmax 3.166345e+03    <NA>  500
#> 283      0 11  1     0 Inf                tmax 2.000000e+00    <NA>  500
#> 284      0 11  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 285      0 11  1     0 Inf           clast.obs 3.574064e-05    <NA>  500
#> 286      0 11  1     0 Inf            lambda.z 9.556086e-02    <NA>  500
#> 287      0 11  1     0 Inf           r.squared 9.999791e-01    <NA>  500
#> 288      0 11  1     0 Inf       adj.r.squared 9.999722e-01    <NA>  500
#> 289      0 11  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 290      0 11  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 291      0 11  1     0 Inf          clast.pred 3.653020e-05    <NA>  500
#> 292      0 11  1     0 Inf           half.life 7.253464e+00    <NA>  500
#> 293      0 11  1     0 Inf          span.ratio 1.654382e+01    <NA>  500
#> 294      0 11  1     0 Inf          aucinf.obs 2.192913e+04    <NA>  500
#> 295      1 11  2     0  24             auclast 1.520481e+04    <NA>  500
#> 296      1 11  2     0 Inf                cmax 4.223442e+03    <NA>  500
#> 297      1 11  2     0 Inf                tmax 1.000000e+00    <NA>  500
#> 298      1 11  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 299      1 11  2     0 Inf           clast.obs 1.658599e-05    <NA>  500
#> 300      1 11  2     0 Inf            lambda.z 9.590341e-02    <NA>  500
#> 301      1 11  2     0 Inf           r.squared 9.999848e-01    <NA>  500
#> 302      1 11  2     0 Inf       adj.r.squared 9.999810e-01    <NA>  500
#> 303      1 11  2     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 304      1 11  2     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 305      1 11  2     0 Inf          clast.pred 1.665633e-05    <NA>  500
#> 306      1 11  2     0 Inf           half.life 7.227555e+00    <NA>  500
#> 307      1 11  2     0 Inf          span.ratio 1.992375e+01    <NA>  500
#> 308      1 11  2     0 Inf          aucinf.obs 1.537818e+04    <NA>  500
#> 309      1 12  1     0  24             auclast 2.288086e+04    <NA>  500
#> 310      1 12  1     0 Inf                cmax 5.426283e+03    <NA>  500
#> 311      1 12  1     0 Inf                tmax 1.500000e+00    <NA>  500
#> 312      1 12  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 313      1 12  1     0 Inf           clast.obs 5.739693e-05    <NA>  500
#> 314      1 12  1     0 Inf            lambda.z 9.219572e-02    <NA>  500
#> 315      1 12  1     0 Inf           r.squared 9.999707e-01    <NA>  500
#> 316      1 12  1     0 Inf       adj.r.squared 9.999633e-01    <NA>  500
#> 317      1 12  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 318      1 12  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 319      1 12  1     0 Inf          clast.pred 5.638430e-05    <NA>  500
#> 320      1 12  1     0 Inf           half.life 7.518214e+00    <NA>  500
#> 321      1 12  1     0 Inf          span.ratio 1.915348e+01    <NA>  500
#> 322      1 12  1     0 Inf          aucinf.obs 2.324308e+04    <NA>  500
#> 323      0 12  2     0  24             auclast 3.274660e+04    <NA>  500
#> 324      0 12  2     0 Inf                cmax 4.500265e+03    <NA>  500
#> 325      0 12  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 326      0 12  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 327      0 12  2     0 Inf           clast.obs 1.192893e-04    <NA>  500
#> 328      0 12  2     0 Inf            lambda.z 9.264301e-02    <NA>  500
#> 329      0 12  2     0 Inf           r.squared 9.999919e-01    <NA>  500
#> 330      0 12  2     0 Inf       adj.r.squared 9.999892e-01    <NA>  500
#> 331      0 12  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 332      0 12  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 333      0 12  2     0 Inf          clast.pred 1.178746e-04    <NA>  500
#> 334      0 12  2     0 Inf           half.life 7.481916e+00    <NA>  500
#> 335      0 12  2     0 Inf          span.ratio 1.603867e+01    <NA>  500
#> 336      0 12  2     0 Inf          aucinf.obs 3.377363e+04    <NA>  500
#> 337      0 13  1     0  24             auclast 2.661068e+04    <NA>  500
#> 338      0 13  1     0 Inf                cmax 4.815076e+03    <NA>  500
#> 339      0 13  1     0 Inf                tmax 2.000000e+00    <NA>  500
#> 340      0 13  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 341      0 13  1     0 Inf           clast.obs 9.344742e-05    <NA>  500
#> 342      0 13  1     0 Inf            lambda.z 8.991307e-02    <NA>  500
#> 343      0 13  1     0 Inf           r.squared 9.999727e-01    <NA>  500
#> 344      0 13  1     0 Inf       adj.r.squared 9.999636e-01    <NA>  500
#> 345      0 13  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 346      0 13  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 347      0 13  1     0 Inf          clast.pred 9.330874e-05    <NA>  500
#> 348      0 13  1     0 Inf           half.life 7.709082e+00    <NA>  500
#> 349      0 13  1     0 Inf          span.ratio 1.556606e+01    <NA>  500
#> 350      0 13  1     0 Inf          aucinf.obs 2.709179e+04    <NA>  500
#> 351      1 13  2     0  24             auclast 1.839950e+04    <NA>  500
#> 352      1 13  2     0 Inf                cmax 5.777191e+03    <NA>  500
#> 353      1 13  2     0 Inf                tmax 1.000000e+00    <NA>  500
#> 354      1 13  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 355      1 13  2     0 Inf           clast.obs 5.534060e-05    <NA>  500
#> 356      1 13  2     0 Inf            lambda.z 9.011662e-02    <NA>  500
#> 357      1 13  2     0 Inf           r.squared 9.999682e-01    <NA>  500
#> 358      1 13  2     0 Inf       adj.r.squared 9.999618e-01    <NA>  500
#> 359      1 13  2     0 Inf lambda.z.time.first 1.200000e+01    <NA>  500
#> 360      1 13  2     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 361      1 13  2     0 Inf          clast.pred 5.460421e-05    <NA>  500
#> 362      1 13  2     0 Inf           half.life 7.691668e+00    <NA>  500
#> 363      1 13  2     0 Inf          span.ratio 2.028169e+01    <NA>  500
#> 364      1 13  2     0 Inf          aucinf.obs 1.865533e+04    <NA>  500
#> 365      1 14  1     0  24             auclast 1.358547e+04    <NA>  500
#> 366      1 14  1     0 Inf                cmax 4.489737e+03    <NA>  500
#> 367      1 14  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 368      1 14  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 369      1 14  1     0 Inf           clast.obs 4.390558e-05    <NA>  500
#> 370      1 14  1     0 Inf            lambda.z 8.757659e-02    <NA>  500
#> 371      1 14  1     0 Inf           r.squared 9.999866e-01    <NA>  500
#> 372      1 14  1     0 Inf       adj.r.squared 9.999832e-01    <NA>  500
#> 373      1 14  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 374      1 14  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 375      1 14  1     0 Inf          clast.pred 4.445670e-05    <NA>  500
#> 376      1 14  1     0 Inf           half.life 7.914754e+00    <NA>  500
#> 377      1 14  1     0 Inf          span.ratio 1.819387e+01    <NA>  500
#> 378      1 14  1     0 Inf          aucinf.obs 1.373685e+04    <NA>  500
#> 379      0 14  2     0  24             auclast 2.069564e+04    <NA>  500
#> 380      0 14  2     0 Inf                cmax 3.629774e+03    <NA>  500
#> 381      0 14  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 382      0 14  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 383      0 14  2     0 Inf           clast.obs 8.703569e-05    <NA>  500
#> 384      0 14  2     0 Inf            lambda.z 8.736114e-02    <NA>  500
#> 385      0 14  2     0 Inf           r.squared 9.999756e-01    <NA>  500
#> 386      0 14  2     0 Inf       adj.r.squared 9.999674e-01    <NA>  500
#> 387      0 14  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 388      0 14  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 389      0 14  2     0 Inf          clast.pred 8.925689e-05    <NA>  500
#> 390      0 14  2     0 Inf           half.life 7.934273e+00    <NA>  500
#> 391      0 14  2     0 Inf          span.ratio 1.512426e+01    <NA>  500
#> 392      0 14  2     0 Inf          aucinf.obs 2.106485e+04    <NA>  500
#> 393      0 15  1     0  24             auclast 4.705248e+04    <NA>  500
#> 394      0 15  1     0 Inf                cmax 6.801036e+03    <NA>  500
#> 395      0 15  1     0 Inf                tmax 3.000000e+00    <NA>  500
#> 396      0 15  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 397      0 15  1     0 Inf           clast.obs 1.637464e-04    <NA>  500
#> 398      0 15  1     0 Inf            lambda.z 9.299096e-02    <NA>  500
#> 399      0 15  1     0 Inf           r.squared 9.999320e-01    <NA>  500
#> 400      0 15  1     0 Inf       adj.r.squared 9.999093e-01    <NA>  500
#> 401      0 15  1     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 402      0 15  1     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 403      0 15  1     0 Inf          clast.pred 1.585577e-04    <NA>  500
#> 404      0 15  1     0 Inf           half.life 7.453920e+00    <NA>  500
#> 405      0 15  1     0 Inf          span.ratio 1.609891e+01    <NA>  500
#> 406      0 15  1     0 Inf          aucinf.obs 4.832842e+04    <NA>  500
#> 407      1 15  2     0  24             auclast 3.544204e+04    <NA>  500
#> 408      1 15  2     0 Inf                cmax 9.339374e+03    <NA>  500
#> 409      1 15  2     0 Inf                tmax 1.500000e+00    <NA>  500
#> 410      1 15  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 411      1 15  2     0 Inf           clast.obs 8.553098e-05    <NA>  500
#> 412      1 15  2     0 Inf            lambda.z 9.361598e-02    <NA>  500
#> 413      1 15  2     0 Inf           r.squared 9.999500e-01    <NA>  500
#> 414      1 15  2     0 Inf       adj.r.squared 9.999400e-01    <NA>  500
#> 415      1 15  2     0 Inf lambda.z.time.first 1.200000e+01    <NA>  500
#> 416      1 15  2     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 417      1 15  2     0 Inf          clast.pred 8.298710e-05    <NA>  500
#> 418      1 15  2     0 Inf           half.life 7.404154e+00    <NA>  500
#> 419      1 15  2     0 Inf          span.ratio 2.106925e+01    <NA>  500
#> 420      1 15  2     0 Inf          aucinf.obs 3.605800e+04    <NA>  500
#> 421      1 16  1     0  24             auclast 1.964559e+04    <NA>  500
#> 422      1 16  1     0 Inf                cmax 5.547706e+03    <NA>  500
#> 423      1 16  1     0 Inf                tmax 1.500000e+00    <NA>  500
#> 424      1 16  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 425      1 16  1     0 Inf           clast.obs 6.351925e-05    <NA>  500
#> 426      1 16  1     0 Inf            lambda.z 8.924039e-02    <NA>  500
#> 427      1 16  1     0 Inf           r.squared 9.999894e-01    <NA>  500
#> 428      1 16  1     0 Inf       adj.r.squared 9.999867e-01    <NA>  500
#> 429      1 16  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 430      1 16  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 431      1 16  1     0 Inf          clast.pred 6.301520e-05    <NA>  500
#> 432      1 16  1     0 Inf           half.life 7.767191e+00    <NA>  500
#> 433      1 16  1     0 Inf          span.ratio 1.853952e+01    <NA>  500
#> 434      1 16  1     0 Inf          aucinf.obs 1.991570e+04    <NA>  500
#> 435      0 16  2     0  24             auclast 2.697415e+04    <NA>  500
#> 436      0 16  2     0 Inf                cmax 4.161112e+03    <NA>  500
#> 437      0 16  2     0 Inf                tmax 3.000000e+00    <NA>  500
#> 438      0 16  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 439      0 16  2     0 Inf           clast.obs 1.123415e-04    <NA>  500
#> 440      0 16  2     0 Inf            lambda.z 8.996109e-02    <NA>  500
#> 441      0 16  2     0 Inf           r.squared 9.999979e-01    <NA>  500
#> 442      0 16  2     0 Inf       adj.r.squared 9.999972e-01    <NA>  500
#> 443      0 16  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 444      0 16  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 445      0 16  2     0 Inf          clast.pred 1.130966e-04    <NA>  500
#> 446      0 16  2     0 Inf           half.life 7.704966e+00    <NA>  500
#> 447      0 16  2     0 Inf          span.ratio 1.557437e+01    <NA>  500
#> 448      0 16  2     0 Inf          aucinf.obs 2.762222e+04    <NA>  500
#> 449      1 17  1     0  24             auclast 1.982688e+04    <NA>  500
#> 450      1 17  1     0 Inf                cmax 5.447778e+03    <NA>  500
#> 451      1 17  1     0 Inf                tmax 1.500000e+00    <NA>  500
#> 452      1 17  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 453      1 17  1     0 Inf           clast.obs 4.083561e-05    <NA>  500
#> 454      1 17  1     0 Inf            lambda.z 9.207758e-02    <NA>  500
#> 455      1 17  1     0 Inf           r.squared 9.999516e-01    <NA>  500
#> 456      1 17  1     0 Inf       adj.r.squared 9.999395e-01    <NA>  500
#> 457      1 17  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 458      1 17  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 459      1 17  1     0 Inf          clast.pred 4.030935e-05    <NA>  500
#> 460      1 17  1     0 Inf           half.life 7.527860e+00    <NA>  500
#> 461      1 17  1     0 Inf          span.ratio 1.912894e+01    <NA>  500
#> 462      1 17  1     0 Inf          aucinf.obs 2.007515e+04    <NA>  500
#> 463      0 17  2     0  24             auclast 2.838540e+04    <NA>  500
#> 464      0 17  2     0 Inf                cmax 4.650235e+03    <NA>  500
#> 465      0 17  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 466      0 17  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 467      0 17  2     0 Inf           clast.obs 7.862104e-05    <NA>  500
#> 468      0 17  2     0 Inf            lambda.z 9.176957e-02    <NA>  500
#> 469      0 17  2     0 Inf           r.squared 9.999844e-01    <NA>  500
#> 470      0 17  2     0 Inf       adj.r.squared 9.999793e-01    <NA>  500
#> 471      0 17  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 472      0 17  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 473      0 17  2     0 Inf          clast.pred 7.926174e-05    <NA>  500
#> 474      0 17  2     0 Inf           half.life 7.553127e+00    <NA>  500
#> 475      0 17  2     0 Inf          span.ratio 1.588746e+01    <NA>  500
#> 476      0 17  2     0 Inf          aucinf.obs 2.897641e+04    <NA>  500
#> 477      1 18  1     0  24             auclast 2.631496e+04    <NA>  500
#> 478      1 18  1     0 Inf                cmax 6.407331e+03    <NA>  500
#> 479      1 18  1     0 Inf                tmax 1.500000e+00    <NA>  500
#> 480      1 18  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 481      1 18  1     0 Inf           clast.obs 6.838782e-06    <NA>  500
#> 482      1 18  1     0 Inf            lambda.z 1.073401e-01    <NA>  500
#> 483      1 18  1     0 Inf           r.squared 9.999576e-01    <NA>  500
#> 484      1 18  1     0 Inf       adj.r.squared 9.999470e-01    <NA>  500
#> 485      1 18  1     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 486      1 18  1     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 487      1 18  1     0 Inf          clast.pred 6.510574e-06    <NA>  500
#> 488      1 18  1     0 Inf           half.life 6.457486e+00    <NA>  500
#> 489      1 18  1     0 Inf          span.ratio 2.229970e+01    <NA>  500
#> 490      1 18  1     0 Inf          aucinf.obs 2.663572e+04    <NA>  500
#> 491      0 18  2     0  24             auclast 3.539986e+04    <NA>  500
#> 492      0 18  2     0 Inf                cmax 4.499100e+03    <NA>  500
#> 493      0 18  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 494      0 18  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 495      0 18  2     0 Inf           clast.obs 1.581891e-05    <NA>  500
#> 496      0 18  2     0 Inf            lambda.z 1.078429e-01    <NA>  500
#> 497      0 18  2     0 Inf           r.squared 9.999480e-01    <NA>  500
#> 498      0 18  2     0 Inf       adj.r.squared 9.999307e-01    <NA>  500
#> 499      0 18  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 500      0 18  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 501      0 18  2     0 Inf          clast.pred 1.580876e-05    <NA>  500
#> 502      0 18  2     0 Inf           half.life 6.427381e+00    <NA>  500
#> 503      0 18  2     0 Inf          span.ratio 1.867012e+01    <NA>  500
#> 504      0 18  2     0 Inf          aucinf.obs 3.657208e+04    <NA>  500
#> 505      0 19  1     0  24             auclast 2.461443e+04    <NA>  500
#> 506      0 19  1     0 Inf                cmax 3.516646e+03    <NA>  500
#> 507      0 19  1     0 Inf                tmax 3.000000e+00    <NA>  500
#> 508      0 19  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 509      0 19  1     0 Inf           clast.obs 1.120752e-03    <NA>  500
#> 510      0 19  1     0 Inf            lambda.z 7.252218e-02    <NA>  500
#> 511      0 19  1     0 Inf           r.squared 9.999962e-01    <NA>  500
#> 512      0 19  1     0 Inf       adj.r.squared 9.999924e-01    <NA>  500
#> 513      0 19  1     0 Inf lambda.z.time.first 9.600000e+01    <NA>  500
#> 514      0 19  1     0 Inf   lambda.z.n.points 3.000000e+00    <NA>  500
#> 515      0 19  1     0 Inf          clast.pred 1.125150e-03    <NA>  500
#> 516      0 19  1     0 Inf           half.life 9.557726e+00    <NA>  500
#> 517      0 19  1     0 Inf          span.ratio 7.533172e+00    <NA>  500
#> 518      0 19  1     0 Inf          aucinf.obs 2.532563e+04    <NA>  500
#> 519      1 19  2     0  24             auclast 1.697932e+04    <NA>  500
#> 520      1 19  2     0 Inf                cmax 4.588825e+03    <NA>  500
#> 521      1 19  2     0 Inf                tmax 1.500000e+00    <NA>  500
#> 522      1 19  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 523      1 19  2     0 Inf           clast.obs 6.157266e-04    <NA>  500
#> 524      1 19  2     0 Inf            lambda.z 7.320386e-02    <NA>  500
#> 525      1 19  2     0 Inf           r.squared 9.999732e-01    <NA>  500
#> 526      1 19  2     0 Inf       adj.r.squared 9.999664e-01    <NA>  500
#> 527      1 19  2     0 Inf lambda.z.time.first 2.400000e+01    <NA>  500
#> 528      1 19  2     0 Inf   lambda.z.n.points 6.000000e+00    <NA>  500
#> 529      1 19  2     0 Inf          clast.pred 6.078001e-04    <NA>  500
#> 530      1 19  2     0 Inf           half.life 9.468724e+00    <NA>  500
#> 531      1 19  2     0 Inf          span.ratio 1.520796e+01    <NA>  500
#> 532      1 19  2     0 Inf          aucinf.obs 1.729700e+04    <NA>  500
#> 533      1 20  1     0  24             auclast 1.365089e+04    <NA>  500
#> 534      1 20  1     0 Inf                cmax 4.126813e+03    <NA>  500
#> 535      1 20  1     0 Inf                tmax 1.000000e+00    <NA>  500
#> 536      1 20  1     0 Inf               tlast 1.680000e+02    <NA>  500
#> 537      1 20  1     0 Inf           clast.obs 3.322179e-06    <NA>  500
#> 538      1 20  1     0 Inf            lambda.z 1.064484e-01    <NA>  500
#> 539      1 20  1     0 Inf           r.squared 9.999136e-01    <NA>  500
#> 540      1 20  1     0 Inf       adj.r.squared 9.998963e-01    <NA>  500
#> 541      1 20  1     0 Inf lambda.z.time.first 1.200000e+01    <NA>  500
#> 542      1 20  1     0 Inf   lambda.z.n.points 7.000000e+00    <NA>  500
#> 543      1 20  1     0 Inf          clast.pred 3.193431e-06    <NA>  500
#> 544      1 20  1     0 Inf           half.life 6.511579e+00    <NA>  500
#> 545      1 20  1     0 Inf          span.ratio 2.395732e+01    <NA>  500
#> 546      1 20  1     0 Inf          aucinf.obs 1.378046e+04    <NA>  500
#> 547      0 20  2     0  24             auclast 2.050570e+04    <NA>  500
#> 548      0 20  2     0 Inf                cmax 3.358273e+03    <NA>  500
#> 549      0 20  2     0 Inf                tmax 2.000000e+00    <NA>  500
#> 550      0 20  2     0 Inf               tlast 1.680000e+02    <NA>  500
#> 551      0 20  2     0 Inf           clast.obs 7.391557e-06    <NA>  500
#> 552      0 20  2     0 Inf            lambda.z 1.061880e-01    <NA>  500
#> 553      0 20  2     0 Inf           r.squared 9.999752e-01    <NA>  500
#> 554      0 20  2     0 Inf       adj.r.squared 9.999670e-01    <NA>  500
#> 555      0 20  2     0 Inf lambda.z.time.first 4.800000e+01    <NA>  500
#> 556      0 20  2     0 Inf   lambda.z.n.points 5.000000e+00    <NA>  500
#> 557      0 20  2     0 Inf          clast.pred 7.244380e-06    <NA>  500
#> 558      0 20  2     0 Inf           half.life 6.527547e+00    <NA>  500
#> 559      0 20  2     0 Inf          span.ratio 1.838363e+01    <NA>  500
#> 560      0 20  2     0 Inf          aucinf.obs 2.087764e+04    <NA>  500