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Summary statement for CYP TDI

cyp_tdi_risk_summary.Rd

Summary statement for CYP TDI

Usage

cyp_tdi_risk_summary(perp, cyp_tdi, cyp_kdeg = cyp_turnover)

Arguments

perp

The perpetrator object.

cyp_tdi

The CYP TDI data as data frame. The following fields are expected:

  • 'name' The perpetrator compound name as character.

  • 'cyp' The CYP enzyme as character.

  • 'ki' The \(K_I\) in \(\mu M\) as numeric.

  • 'kinact' The \(k_{inact}\) in 1/h as numeric.

  • 'source' Optional source information as character,

cyp_kdeg

The CYP turnover data as data frame. Defaults to the built-in reference data, cyp_turnover.

Value

Markdown-formatted text output.

Examples

cyp_tdi_risk_summary(examplinib_parent, examplinib_cyp_tdi_data)
#> [1] "* examplinib has a clinical risk for time-dependent inhibition of CYP3A4"
cyp_tdi_risk_summary(examplinib_compounds, examplinib_cyp_tdi_data)
#> [1] "* examplinib has a clinical risk for time-dependent inhibition of CYP3A4"